| Type | Description |
|---|---|
| Definition | large conductance mechanosensitive channel |
| Date | Results | Publications |
|---|---|---|
| 2019-09-07 10:13:00 | The study described a novel class of MscL mutations that were correlated with the thermodynamic stability of the MscL structure. | 31143940 |
| 2019-01-12 10:51:00 | Collectively, the findings indicate that MscL-dependent protein excretion is positively regulated in response to both osmotic stress and arfA-mediated translational stress. | 29382730 |
| 2018-12-22 10:44:00 | Because MscL opens to tension in the lipid bilayer, requiring no other proteins or ligands, it could be developed into a general noninvasive sonogenetic tool to manipulate the activities of neurons or other cells and potential nanodevices. | 29916253 |
| 2018-09-08 10:23:00 | the amphipathic N-terminal helix of MscL acts as a crucial structural element during tension-induced gating, both stabilizing the closed state and coupling the channel to the membrane | 27329693 |
| 2017-10-14 13:09:00 | More importantly, the FE model indicates that to fully operate an MscL nanovalve by pulling directly on the N-terminus and bottom of TM1, gain-of-function (GOF) mutants (e.g., G22N MscL) would have to be employed rather than the WT MscL channel. | 28859093 |
| Type | IDs |
|---|---|
| Synonymous | ECK3277, yhdC |
| Gene |
UniProtKB-ID:
MSCL_ECOLI
UniprotKB:
P0A742
UniParc:
UPI000012F5DC
EMBL:
U00096,
L29458,
U18997,
AP009048,
X52114,
U08371
EnsemblGenome:
b3291,
BAE78001
KO:
ecj:JW3252,
eco:b3291
|
| Nucleutide sequences |
EMBL-CDS:
CAA36360.1,
AAA17745.1,
BAE78001.1,
AAC76316.1,
AAA58088.1,
AAA24771.1
EnsemblGenome_TRS:
BAE78001,
AAC76316
|
| Protein sequencees |
EnsemblGenome_PRO:
BAE78001,
AAC76316
RefSeq:
NP_417749.1
|
| Others |
UniRef100:
UniRef100_A7ZSH9
UniRef90:
UniRef90_A8AQI5
UniRef50:
UniRef50_B4F1L3
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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