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947755 cyaA

947755

cyaA

adenylate cyclase

protein-coding

Escherichia coli str. K-12 substr. MG1655

基因描述

Type Description
Definition adenylate cyclase

研究结论

Date Results Publications
2018-07-21 11:27:00 the CyaA(N600Y) mutant has a transcriptome indicative of increased CRP activity, pointing to an unknown role for CyaA and / or cAMP in gene expression..We show that the large scale transcriptomic changes in the topoisomerase I (FusA(A608E)-TopA(S180L)) mutant likely result from increased negative supercoiling in the cell. 29046437
2010-01-21 00:00:00 The transcription of the cyaR gene is stringently controlled by cAMP-cAMP receptor protein and, unexpectedly, cyaR expression is also up-regulated, directly or indirectly, by sigma(E). 18619465
2010-01-21 00:00:00 deletion of the catabolite repression regulators Crp and Cya resulted in a pronounced slow-growth phenotype but had only a nonspecific effect on the actual flux distribution. 15838044
2010-01-21 00:00:00 RNase LS regulates Crp-cAMP concentration by degrading the cyaA transcripts. 19019153
2010-01-21 00:00:00 A model for regulation of adenylate cyclase (AC) activity involves the interaction of the regulatory domain of AC with both a regulatory factor and enzyme component IIAGlc of the bacterial phosphoenolpyruvate phosphotransferase system. 16407219

名称对应

Type IDs
Synonymous ECK3800, cya
Gene
UniProtKB-ID: CYAA_ECOLI
UniprotKB: P00936
UniParc: UPI00001681EF
EMBL: X66782, U00096, M87049, AP009048, X01653
EnsemblGenome: BAE77495, b3806
KO: eco:b3806, ecj:JW3778
Nucleutide sequences
EMBL-CDS: CAA25817.1, BAE77495.1, AAA67602.1, CAA47280.1, AAC76809.1
EnsemblGenome_TRS: AAC76809, BAE77495
Protein sequencees
EnsemblGenome_PRO: BAE77495, AAC76809
RefSeq: NP_418250.1
Others
UniRef100: UniRef100_P00936
UniRef90: UniRef90_P00936
UniRef50: UniRef50_P00936

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