| Type | Description |
|---|---|
| Definition | N-acetylneuraminate lyase |
| Date | Results | Publications |
|---|---|---|
| 2011-07-02 11:10:00 | analysis of modulation of substrate specificities of D-sialic acid aldolase through single mutations of Val-251 | 21270125 |
| 2010-12-11 10:58:00 | A comparison of mutant and wild-type nanA structures, in combination with the specificity profiles of the variants, reveals subtle differences that explain the details of the substrate specificity changes. | 20826162 |
| 2010-02-08 11:48:00 | Results describe the structure of a mutant variant of Escherichia coli N-acetyl-d-neuraminic acid lyase (NAL), E192N, in complex with pyruvate in a new crystal form. | 19923724 |
| 2010-01-21 00:00:00 | the dimer-dimer interface of NAL is intolerant to mutation and essential for functional expression. | 19646958 |
| 2007-11-05 21:38:00 | N-terminus verified by Edman degradation on complete protein | 3909108 |
| Type | IDs |
|---|---|
| Synonymous | ECK3214, npl |
| Gene |
UniProtKB-ID:
NANA_ECOLI
UniprotKB:
P0A6L4
UniParc:
UPI0000157414
EMBL:
X03345,
U00096,
U18997,
AP009048,
D00067
EnsemblGenome:
b3225,
BAE77268
KO:
ecj:JW3194,
eco:b3225
|
| Nucleutide sequences |
EMBL-CDS:
CAA27051.1,
BAE77268.1,
AAC76257.1,
AAA58027.1,
BAA00046.1
EnsemblGenome_TRS:
BAE77268,
AAC76257
|
| Protein sequencees |
EnsemblGenome_PRO:
AAC76257,
BAE77268
RefSeq:
NP_417692.1
|
| Others |
UniRef100:
UniRef100_A7ZSB8
UniRef90:
UniRef90_Q8FD58
UniRef50:
UniRef50_Q8FD58
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 21270125 |
Modulation of substrate specificities of D-sialic acid aldolase through single mutations of Val-251. J Biol Chem Chien-Yu Chou , Tzu-Ping Ko , Kuan-Jung Wu , Kai-Fa Huang , Chun-Hung Lin , Chi-Huey Wong , Andrew H-J Wang |
2011-04-22 | - |
| 20826162 |
J. Mol. Biol. Ivan Campeotto , Amanda H Bolt , Thomas A Harman , Caitriona Dennis , Chi H Trinh , Simon E V Phillips , Adam Nelson , Arwen R Pearson , Alan Berry |
2010-11-19 |
nanA
|
| 19923724 |
Acta Crystallogr Sect F Struct Biol Cryst Commun Ivan Campeotto , Stephen B Carr , Chi H Trinh , Adam S Nelson , Alan Berry , Simon E V Phillips , Arwen R Pearson |
2009-11-01 | - |
| 19646958 |
Biochem. Biophys. Res. Commun. Sean R A Devenish , Juliet A Gerrard |
2009-10-09 |
nanA
|
| 18852508 |
The diversity of lysine-acetylated proteins in Escherichia coli. J. Microbiol. Biotechnol. Byung Jo Yu , Jung Ae Kim , Jeong Hee Moon , Seong Eon Ryu , Jae-Gu Pan |
2008-09-01 |
sslE,
talB,
dnaK,
carB,
aceF,
lpd,
dapD,
acnB,
tsf,
pepD,
eno,
gpmA,
tig,
htpG,
serA,
fldA,
sucB,
sucD,
gltA,
rpsA,
cobB,
icd,
prs,
kdsA,
purU,
adhE,
topA,
tpx,
pyrG,
grxD,
aspS,
motB,
yeeN,
cysK,
crr,
rimJ,
cysS,
guaB,
pka,
grpE,
recA,
pgk,
tktA,
ahpF,
rpoD,
fadH,
pnp,
gapA,
ftsH,
glmM,
nanA,
rplQ,
rpsK,
rpsD,
rpoA,
rplE,
rplD,
tufA,
fusA,
mdh,
crp,
rpsB,
asd,
cysE,
tnaA,
atpD,
rho,
sodA,
tufB,
rplA,
aceA,
pgi,
ssb,
acs,
groL,
rplI,
rpsR,
rpsF,
ppa,
pyrB,
pepA,
tsr,
guaC,
folE
|
| 18304323 |
Protein abundance profiling of the Escherichia coli cytosol. BMC Genomics Yasushi Ishihama , Thorsten Schmidt , Juri Rappsilber , Matthias Mann , F Ulrich Hartl , Michael J Kerner , Dmitrij Frishman |
2008-01-01 | - |
| 16397293 |
Escherichia coli K-12: a cooperatively developed annotation snapshot--2005. Nucleic Acids Res. Monica Riley , Takashi Abe , Martha B Arnaud , Mary K B Berlyn , Frederick R Blattner , Roy R Chaudhuri , Jeremy D Glasner , Takashi Horiuchi , Ingrid M Keseler , Takehide Kosuge , Hirotada Mori , Nicole T Perna , Guy Plunkett , Kenneth E Rudd , Margrethe H Serres , Gavin H Thomas , Nicholas R Thomson , David Wishart , Barry L Wanner |
2006-01-01 |
pmrR,
yfaS,
torI,
yaeP,
ykfH,
ykgO,
ylcG,
rzoD,
ybdZ,
cydX,
gnsA,
insA,
ymgF,
ymiA,
yciX,
rzoR,
ynfO,
yniD,
yobH,
yoeF,
yoeB,
yohO,
arnE,
ypdJ,
ypeB,
ypfN,
ypjJ,
arfA,
yheV,
ysaB,
sgcB,
yjhX,
ytjA,
yibT,
yicS,
yidD,
yifL,
ghoT,
yjjZ,
mntS,
iroK,
yifN,
wecF,
yigE,
blr,
yggP,
cpxP,
ygaY,
hdfR,
thiS,
yedN,
greB,
rtcA,
smf,
ygcU,
ypjK,
hokE,
sslE,
glcF,
glcE,
glvC,
yhaM,
tdcG,
ytfR,
yehH,
hokB,
ldrD,
hokA,
ldrA,
ldrB,
ecnA,
ecnB,
gapC,
yfjD,
yhdP,
yjjV,
cysW,
hokC,
ghxQ,
tatD,
yjdP,
cutC,
nirC,
frlC,
aroK,
gntU,
yedS,
dgoD,
dgoA,
dgoR,
yigL,
ldrC,
ylbE,
ydbJ,
yeiW,
yehK,
yaiX,
yoeA,
yneM
|
| 16738553 |
Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Mol. Syst. Biol. Koji Hayashi , Naoki Morooka , Yoshihiro Yamamoto , Katsutoshi Fujita , Katsumi Isono , Sunju Choi , Eiichi Ohtsubo , Tomoya Baba , Barry L Wanner , Hirotada Mori , Takashi Horiuchi |
2006-01-01 |
pmrR,
torI,
yaeP,
ykfH,
ykgO,
ylcG,
rzoD,
ybdZ,
cydX,
gnsA,
insA,
ymgF,
ymiA,
yciX,
rzoR,
ynfO,
yniD,
yobH,
yoeB,
yohO,
arnE,
ypeB,
ypfN,
ypjJ,
arfA,
yheV,
ysaB,
sgcB,
yjhX,
ytjA,
yibT,
yicS,
yidD,
yifL,
ghoT,
yjjZ,
mntS,
iroK,
wecF,
yigE,
blr,
yggP,
cpxP,
hdfR,
thiS,
greB,
rtcA,
smf,
ygcU,
ypjK,
hokE,
sslE,
glcF,
glcE,
yhaM,
tdcG,
ytfR,
hokB,
ldrD,
hokA,
ldrA,
ldrB,
ecnA,
ecnB,
yfjD,
yhdP,
yjjV,
cysW,
hokC,
ghxQ,
tatD,
yjdP,
cutC,
nirC,
frlC,
aroK,
gntU,
dgoD,
dgoA,
dgoR,
yigL,
ldrC,
ylbE,
ydbJ,
yeiW,
yehK,
yneM,
ykfM,
ylcI,
yciY,
yncL,
ylcH,
ynhF,
yciZ,
ydgU,
ypfM,
ymgI,
ymgJ,
dinQ
|
| 15967977 |
Directed evolution of D-sialic acid aldolase to L-3-deoxy-manno-2-octulosonic acid (L-KDO) aldolase. Proc. Natl. Acad. Sci. U.S.A. Che-Chang Hsu , Zhangyong Hong , Masaru Wada , Dirk Franke , Chi-Huey Wong |
2005-06-28 |
nanA
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员