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947694 obgE

947694

obgE

GTPase ObgE

protein-coding

Escherichia coli str. K-12 substr. MG1655

基因描述

Type Description
Definition GTPase ObgE

研究结论

Date Results Publications
2020-04-04 11:58:00 The data suggest that GDP or ppGpp binding is required but not sufficient for ObgE to activate expression of hokB, ultimately leading to persistence. 31498933
2017-06-03 11:38:00 Biophysical analysis, using small angle X-ray scattering and multi-angle light scattering experiments, revealed that ObgE is a monomer in solution, regardless of the bound nucleotide. In contrast to recent suggestions, our biochemical analyses further indicate that ObgE is neither activated by K(+) ions nor by homodimerization. 28223358
2017-05-27 10:49:00 obgE is cotranscribed with ribosomal protein genes rplU and rpmA. 27137500
2016-08-06 10:18:00 The authors report that expression of a mutant isoform of the essential GTPase ObgE causes rapid loss of viability in Escherichia coli. 26695632
2015-05-30 10:18:00 ObgE might act as a checkpoint in final stages of the 50S subunit assembly under normal growth conditions, and, as a (p)ppGpp effector, might also have a regulatory role in the production of the 50S subunit under stressed conditions. 24844575

名称对应

Type IDs
Synonymous ECK3172, cgtA, obg, yhbZ
Gene
UniProtKB-ID: OBG_ECOLI
UniprotKB: P42641
UniParc: UPI000013B1CF
EMBL: AP009048, U18997, U00096
EnsemblGenome: b3183, BAE77227
KO: eco:b3183, ecj:JW3150
Nucleutide sequences
EMBL-CDS: BAE77227.1, AAA57984.1, AAC76215.1
EnsemblGenome_TRS: BAE77227, AAC76215
Protein sequencees
EnsemblGenome_PRO: BAE77227, AAC76215
RefSeq: NP_417650.1
Others
UniRef100: UniRef100_B1XHF9
UniRef90: UniRef90_A8AQ74
UniRef50: UniRef50_Q9KUS8

全选

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研究热度

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