| Type | Description |
|---|---|
| Definition | DNA-binding transcriptional dual regulator MarA |
| Date | Results | Publications |
|---|---|---|
| 2020-04-04 13:00:00 | MarA is a regulator of biofilm formation. Control is mediated by binding of MarA to the intergenic region upstream of the ycgZ-ymgABC operon. | 31518447 |
| 2019-03-02 10:10:00 | MarA controls a variety of stress response genes. We modify its half-life either by knocking down the protease that targets it via CRISPRi or by engineering MarA to protect it from degradation. Our experimental and analytical results indicate that active degradation can impact both the rate of coordination and the maximum coordination that downstream genes can achieve. | 30589845 |
| 2018-09-15 10:25:00 | Transcription factors MarR and MarA confer multidrug resistance in enteric bacteria by modulating efflux pump and porin expression. Here, the authors show that MarA also upregulates genes required for lipid trafficking and DNA repair, thus reducing antibiotic entry and quinolone-induced DNA damage. | 29133912 |
| 2014-05-17 15:01:00 | Genetic defects in SoxS, MarA, or AcrB underlie superoxide-mediated protection of Escherichia coli from antimicrobials. | 23979754 |
| 2014-02-01 10:08:00 | MarB encodes a periplasmic protein which reduces the transcription rate of marA. | 23710538 |
| Type | IDs |
|---|---|
| Synonymous | ECK1524, cfxB, inaR, nfxC, norB, soxQ |
| Gene |
UniProtKB-ID:
MARA_ECOLI
UniprotKB:
P0ACH5
UniParc:
UPI000016F2D6
EMBL:
L06966,
U00096,
AP009048,
M96235
EnsemblGenome:
BAA15221,
b1531
KO:
ecj:JW5249,
eco:b1531
|
| Nucleutide sequences |
EMBL-CDS:
AAA24113.1,
AAC74604.2,
BAA15221.2,
AAC16395.1
EnsemblGenome_TRS:
AAC74604,
BAA15221
|
| Protein sequencees |
EnsemblGenome_PRO:
AAC74604,
BAA15221
RefSeq:
NP_416048.2
|
| Others |
UniRef100:
UniRef100_P0ACH6
UniRef90:
UniRef90_P0ACH6
UniRef50:
UniRef50_P0ACH6
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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