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947500 mqsR

947500

mqsR

mRNA interferase/toxin of the MqsR-MqsA toxin-antitoxin system

protein-coding

Escherichia coli str. K-12 substr. MG1655

基因描述

Type Description
Definition mRNA interferase/toxin of the MqsR-MqsA toxin-antitoxin system

研究结论

Date Results Publications
2019-01-12 10:38:00 Fragmentation of Escherichia coli mRNA by MazF and MqsR. 30315853
2016-10-29 11:58:00 findings show that the cyclic AMP receptor protein (CRP) indirectly upregulates mqsRA transcription; also show that CRP plays an important role in antibiotic persistence, which seems to be partially mediated through MqsRA 26408451
2013-04-06 10:50:00 Therefore, the more toxic MqsR increases persistence by decreasing the ability of the cell to respond to antibiotic stress through its RpoS-based regulation of acid resistance, multidrug resistance and osmotic resistance systems. 22221537
2011-01-29 11:24:00 MqsA protein was cocrystallized with a 26-mer duplex DNA corresponding to the palindromic region of the mqsRA promoter 20823526
2010-10-23 11:13:00 The MqsR/MqsA TA system controls cell physiology via its own toxicity as well as through its regulation of another toxin, CspD. 20105222

名称对应

Type IDs
Synonymous ECK3013, ygiU
Gene
UniProtKB-ID: MQSR_ECOLI
UniprotKB: Q46865
UniParc: UPI000013B0CD
EMBL: U28377, AP009048, U00096
EnsemblGenome: BAE77078, b3022
KO: eco:b3022, ecj:JW2990
Nucleutide sequences
EMBL-CDS: BAE77078.1, AAA69190.1, AAC76058.1
EnsemblGenome_TRS: AAC76058, BAE77078
Protein sequencees
EnsemblGenome_PRO: BAE77078, AAC76058
RefSeq: NP_417494.1
Others
UniRef100: UniRef100_Q46865
UniRef90: UniRef90_Q46865
UniRef50: UniRef50_Q46865

全选

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研究热度

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