| Type | Description |
|---|---|
| Definition | Rho associated coiled-coil containing protein kinase 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:13:00 | The Rho kinase 2 (ROCK2)-specific inhibitor KD025 ameliorates the development of pulmonary arterial hypertension. | 33160621 |
| 2020-12-19 13:43:00 | Selective dysregulation of ROCK2 activity promotes aberrant transcriptional networks in ABC diffuse large B-cell lymphoma. | 32753663 |
| 2020-12-12 13:28:00 | Serum ROCK2, miR-300 and miR-450b-5p levels in two different clinical phenotypes of multiple sclerosis: Relation to patient disability and disease progression. | 32781341 |
| 2020-10-10 13:02:00 | lncRNA HAND2AS1 mediates the downregulation of ROCK2 in hepatocellular carcinoma and inhibits cancer cell proliferation, migration and invasion. | 31922232 |
| 2020-10-10 13:00:00 | Inhibition of ROCK2 alleviates renal fibrosis and the metabolic disorders in the proximal tubular epithelial cells. | 32490513 |
| Type | IDs |
|---|---|
| Synonymous | ROCK-II |
| Gene |
UniProtKB-ID:
ROCK2_HUMAN,
Q14DU5_HUMAN,
A0A2P9DU05_HUMAN
UniprotKB:
O75116,
Q14DU5,
A0A2P9DU05
UniParc:
UPI0000DA6B80,
UPI000034ECB0
EMBL:
AB014519,
AC099344,
BC111801,
AC018463,
LT978485,
D87931
Ensembl:
ENSG00000134318
KO:
hsa:9475
|
| Nucleutide sequences |
EMBL-CDS:
AAX93049.1,
AAY14825.1,
BAA75636.1,
BAA31594.2,
AAI11802.1,
SPB63065.1
Ensembl_TRS:
ENST00000315872,
ENST00000616279
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000317985,
ENSP00000481789
RefSeq:
XP_005246247.1,
NP_004841.2,
XP_011508719.1,
XP_016860868.1,
NP_001308572.1,
XP_016860867.1
|
| Others |
UniRef100:
UniRef100_Q14DU5,
UniRef100_O75116
UniRef90:
UniRef90_O75116
UniRef50:
UniRef50_O75116
UniGene:
Hs.681743
CCDS:
CCDS42654.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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