| Type | Description |
|---|---|
| Definition | leucine--tRNA ligase |
| Date | Results | Publications |
|---|---|---|
| 2020-10-24 14:00:00 | Mechanism of discrimination of isoleucyl-tRNA synthetase against nonproteinogenic alpha-aminobutyrate and its fluorinated analogues. | 31486189 |
| 2017-12-16 10:53:00 | Zinc is the molecular "switch" that controls the catalytic cycle of bacterial leucyl-tRNA synthetase | 25450019 |
| 2017-07-08 12:40:00 | In vitro assays showed that acetyl-phosphate nonenzymatically acetylates EcLeuRS and EcArgRS and suggested that the sirtuin class deacetylase CobB might regulate acetylation of these two enzymes. These findings imply a potential regulatory role for Lys acetylation in controlling the activity of aminoacyl-tRNA synthetases and thus protein synthesis. | 28455447 |
| 2014-10-04 10:58:00 | The prime biological function of LeuRS editing is to prevent mis-incorporation of the non-standard amino acid norvaline. | 24935946 |
| 2013-07-27 12:24:00 | This work provides an assessment of how intra-molecular translocation of the tRNA CCA-tail balances the aminoacylation and editing activities of LeuRS. | 23585282 |
| Type | IDs |
|---|---|
| Synonymous | ECK0635, syl |
| Gene |
UniProtKB-ID:
SYL_ECOLI
UniprotKB:
P07813
UniParc:
UPI000013655E
EMBL:
U00096,
AP009048,
U82598,
X06331
EnsemblGenome:
BAA35289,
b0642
KO:
ecj:JW0637,
eco:b0642
|
| Nucleutide sequences |
EMBL-CDS:
AAC73743.1,
BAA35289.1,
CAA29642.1,
AAB40843.1
EnsemblGenome_TRS:
AAC73743,
BAA35289
|
| Protein sequencees |
EnsemblGenome_PRO:
AAC73743,
BAA35289
RefSeq:
NP_415175.1
|
| Others |
UniRef100:
UniRef100_C4ZWC9
UniRef90:
UniRef90_C4ZWC9
UniRef50:
UniRef50_Q9PBG8
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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