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947362 xerD

947362

xerD

site-specific recombinase

protein-coding

Escherichia coli str. K-12 substr. MG1655

基因描述

Type Description
Definition site-specific recombinase

研究结论

Date Results Publications
2018-07-07 12:06:00 FtsKgamma interacts with the C-terminal domain of XerD, above a cleft where XerC is thought to bind. We present a model for activation of recombination based on structural data. 27708355
2017-05-13 20:28:00 e reveal a physical and functional interaction between Topo IV and the XerCD recombinases acting at the dif site. This interaction is modulated by MatP, a protein involved in the organization of the Ter macrodomain. These results show that Topo IV, XerCD/dif and MatP are part of a network dedicated to the final step of chromosome management during the cell cycle. 27171414
2016-01-16 11:10:00 FtsK translocase has a role in assembly, translocation, and activation of XerCD-dif recombination 26324908
2014-01-04 10:49:00 Data indicate that the arrival of the FtsK translocase at an initial synaptic complex, forming a transient activated complex in which XerD exchanged a pair of strands to form an Holliday junctions (HJ) intermediate for catalysis by XerC. 24101525
2010-01-21 00:00:00 A 62-amino-acid fragment of FtsK(C) interacts directly with the XerD C-terminus in order to stimulate the cleavage by XerD of BSN, a dif-DNA suicide substrate containing a nick in the 'bottom' strand. 16553881

名称对应

Type IDs
Synonymous ECK2889, xprB
Gene
UniProtKB-ID: XERD_ECOLI
UniprotKB: P0A8P8
UniParc: UPI000003EB06
EMBL: U00096, AP009048, U28375, M54884
EnsemblGenome: BAE76959, b2894
KO: ecj:JW2862, eco:b2894
Nucleutide sequences
EMBL-CDS: BAE76959.1, AAC75932.1, AAA62787.1, AAA83075.1
EnsemblGenome_TRS: AAC75932, BAE76959
Protein sequencees
EnsemblGenome_PRO: BAE76959, AAC75932
RefSeq: NP_417370.1
Others
UniRef100: UniRef100_P0A8P9
UniRef90: UniRef90_Q8X574
UniRef50: UniRef50_Q9KPE9

全选

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