| Type | Description |
|---|---|
| Definition | endoribonuclease toxin MazF |
| Date | Results | Publications |
|---|---|---|
| 2019-07-27 13:06:00 | The increase in growth rate heterogeneity is governed by the MazE antitoxin, and tuned by the MazF-dependent mazF mRNA cleavage. | 29432616 |
| 2019-05-18 12:37:00 | The authors show that the mRNAs of almost all of them are characterized by the presence of an ACA site up to 100 nucleotides upstream of the AUG initiator. Therefore, under stressful conditions, induced MazF processes mRNAs that are translated by stress-induced translation machinery. | 30914510 |
| 2019-03-09 11:15:00 | MazF rapidly disrupts ribosome biogenesis by targeting both ribosomal protein transcripts and rRNA precursors, helping to inhibit cell growth. | 29861158 |
| 2019-01-12 10:38:00 | results show that both toxins cleave mRNA independently of the recognition site position and MazF freely cleaves transcripts of the proposed MazF regulon within coding sequences. | 30315853 |
| 2017-09-16 10:52:00 | By removing the 3-terminus of the 16S rRNA, MazF generates specialized ribosomes that selectively translate mRNAs likewise processed by MazF. | 27789694 |
| Type | IDs |
|---|---|
| Synonymous | ECK2776, chpA, chpAK |
| Gene |
UniProtKB-ID:
MAZF_ECOLI
UniprotKB:
P0AE70
UniParc:
UPI00001278B1
EMBL:
D16450,
U00096,
J04039,
AP009048,
U29580
EnsemblGenome:
BAE76856,
b2782
KO:
eco:b2782,
ecj:JW2753
|
| Nucleutide sequences |
EMBL-CDS:
AAA69292.1,
AAC75824.1,
BAA03918.1,
BAE76856.1,
AAA03239.1
EnsemblGenome_TRS:
AAC75824,
BAE76856
|
| Protein sequencees |
EnsemblGenome_PRO:
AAC75824,
BAE76856
RefSeq:
NP_417262.1
|
| Others |
UniRef100:
UniRef100_P0AE71
UniRef90:
UniRef90_P0AE71
UniRef50:
UniRef50_P0AE71
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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