| Type | Description |
|---|---|
| Definition | GDP/GTP pyrophosphokinase |
| Date | Results | Publications |
|---|---|---|
| 2019-10-19 12:32:00 | The results reveal that nitrogen-starved Escherichia coli synthesizes (p)ppGpp and forms a higher percentage of persister cells than nonstarved cells and that both NtrC and RelA are important for these processes. | 30420451 |
| 2019-07-20 10:25:00 | The A-site finger structural element of 23S rRNA helix 38 is crucial for RelA binding to the ribosome and consequent activation. | 29390134 |
| 2019-06-08 12:34:00 | Deleting dksA, which encodes a regulator of the stringent response to nutrient starvation, decreases growth under glucose phosphate stress conditions. The stringent response alarmone regulator ppGpp (synthesized by RelA and SpoT) also contributes to recovery from glucose phosphate stress: as with dksA, mutating relA and spoT worsens the growth defect of an sgrS mutant during stress. | 28986375 |
| 2019-01-19 10:26:00 | Amino acid starvation leads to loading of cognate tRNARelA complexes at vacant ribosomal A-sites. In turn, RelA is activated and synthesizes (p)ppGpp. | 29625042 |
| 2017-11-18 11:32:00 | The boomerang-shaped RelA with a wingspan of more than 100 A wraps around the A/R (30S A-site/RelA-bound) tRNA. | 27434674 |
| Type | IDs |
|---|---|
| Synonymous | ECK2778, RC |
| Gene |
UniProtKB-ID:
RELA_ECOLI
UniprotKB:
P0AG20
UniParc:
UPI0000133659
EMBL:
U29580,
J04039,
AP009048,
U00096
EnsemblGenome:
b2784,
BAE76858
KO:
ecj:JW2755,
eco:b2784
|
| Nucleutide sequences |
EMBL-CDS:
AAC75826.1,
AAA69294.1,
AAA03237.1,
BAE76858.1
EnsemblGenome_TRS:
AAC75826,
BAE76858
|
| Protein sequencees |
EnsemblGenome_PRO:
BAE76858,
AAC75826
RefSeq:
NP_417264.1
|
| Others |
UniRef100:
UniRef100_P0AG22
UniRef90:
UniRef90_P0AG22
UniRef50:
UniRef50_P0AG22
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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