| Type | Description |
|---|---|
| Definition | CRISPR-associated endonuclease/helicase Cas3 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:26:00 | Glycine Cleavage System and cAMP Receptor Protein Co-Regulate CRISPR/cas3 Expression to Resist Bacteriophage. | 31941083 |
| 2020-07-04 12:24:00 | We found that Cas3-stimulated uncontrolled plasmid replication occurs only at 37 degrees C, irrespective of the genotype of the analysed mutants, and dependent on Cas3 helicase function. | 31095294 |
| 2017-09-09 12:28:00 | Cas3-derived target DNA degradation fragments fuel primed CRISPR adaptation. | 27546790 |
| 2016-10-22 11:03:00 | Transcription and stability of cas3 in Deltahns cells is limiting for resistance to phage. | 26956996 |
| 2016-02-27 11:42:00 | These results establish Cas1-Cas2 as a trans-acting factor necessary for the recruitment and regulation of Cas3 at escape targets. Based on findings, a mechanistic framework is proposed describing how Cascade, Cas1, Cas2, and Cas3 work together to process and disable foreign genetic elements. | 26522594 |
| Type | IDs |
|---|---|
| Synonymous | ECK2756, ygcB |
| Gene |
UniProtKB-ID:
CAS3_ECOLI
UniprotKB:
P38036
UniParc:
UPI000013B038
EMBL:
U29579,
U00096,
Y07525,
AP009048
EnsemblGenome:
b2761,
BAE76838
KO:
eco:b2761,
ecj:JW2731
|
| Nucleutide sequences |
EMBL-CDS:
AAC75803.1,
BAE76838.1,
AAA69271.1
EnsemblGenome_TRS:
AAC75803,
BAE76838
|
| Protein sequencees |
EnsemblGenome_PRO:
AAC75803,
BAE76838
RefSeq:
NP_417241.1
|
| Others |
UniRef100:
UniRef100_P38036
UniRef90:
UniRef90_P38036
UniRef50:
UniRef50_P38036
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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