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947213 cas2

947213

cas2

CRISPR-associated endoribonuclease Cas2

protein-coding

Escherichia coli str. K-12 substr. MG1655

基因描述

Type Description
Definition CRISPR-associated endoribonuclease Cas2

研究结论

Date Results Publications
2019-03-02 12:37:00 The presence of stx-phage was related to the molecular distribution of CRISPR in E. coli O26ratioH11 or NM. CRISPR might be a valuable biomarker to identify strains with high virulent potential. 28738471
2018-02-10 10:46:00 These results explain how the Cas1-Cas2 CRISPR integrase recognizes a sequence-dependent DNA structure to ensure site-selective CRISPR array expansion during the initial step of bacterial adaptive immunity. 28729350
2017-08-12 12:34:00 to form a long-lived ternary complex containing Cas1-Cas2, the acceptor DNA must carry a CRISPR locus, and the protospacer must not contain 3-single-stranded overhangs longer than 5 bases. 28034956
2017-06-10 10:58:00 Asymmetric positioning of Cas1-Cas2 complex and Integration Host Factor induced DNA bending guide the unidirectional homing of protospacer in CRISPR-Cas type I-E system. 27899566
2016-02-27 11:42:00 These results establish Cas1-Cas2 as a trans-acting factor necessary for the recruitment and regulation of Cas3 at escape targets. Based on findings, a mechanistic framework is proposed describing how Cascade, Cas1, Cas2, and Cas3 work together to process and disable foreign genetic elements. 26522594

名称对应

Type IDs
Synonymous ECK2749, ygbF
Gene
UniProtKB-ID: CAS2_ECOLI
UniprotKB: P45956
UniParc: UPI000013B026
EMBL: U00096, AP009048, U29579, M27059
EnsemblGenome: b2754, BAE76831
KO: eco:b2754, ecj:JW5438
Nucleutide sequences
EMBL-CDS: AAA69264.1, BAE76831.1, AAC75796.2
EnsemblGenome_TRS: BAE76831, AAC75796
Protein sequencees
EnsemblGenome_PRO: AAC75796, BAE76831
RefSeq: NP_417234.2
Others
UniRef100: UniRef100_P45956
UniRef90: UniRef90_P45956
UniRef50: UniRef50_P45956

全选

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研究热度

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