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947206 mutS

947206

mutS

DNA mismatch repair protein MutS

protein-coding

Escherichia coli str. K-12 substr. MG1655

基因描述

Type Description
Definition DNA mismatch repair protein MutS

研究结论

Date Results Publications
2021-03-13 13:22:00 Responses of DNA Proteins to a Stable G-Quadruplex Embedded into a DNA Duplex Structure. 33233554
2020-03-21 10:35:00 we observe that a single residue substitution (R168C) results in a high rate of head-to-tail (tandem) short sequence duplications, which are independent of existing sequence repeats. Finally, we show that the unique mutation spectrum of topA mutants enhances the emergence of antibiotic resistance in comparison to mismatch-repair (mutS) mutators, and leads to new resistance genotypes. 31777935
2019-12-07 10:38:00 Sharp kinking of a coiled-coil in MutS allows DNA binding and release. 31372631
2017-06-24 12:40:00 Mechanism for verification of mismatched and homoduplex DNAs by nucleotides-bound MutS analyzed by molecular dynamics simulations has been reported. 27238299
2017-04-01 10:44:00 The assembly of an EcMutS-EcMutL-EcMutH search complex illustrates how sequential stable sliding clamps can modulate one-dimensional diffusion mechanics along the DNA to direct mismatch repair 27851738

名称对应

Type IDs
Synonymous ECK2728, ant, fdv, plm
Gene
UniProtKB-ID: MUTS_ECOLI
UniprotKB: P23909
UniParc: UPI000012FA69
EMBL: U29579, AF002006, AF002009, AF001993, AF001998, AF001999, AF002007, AF001994, AF001987, AF002002, AF002001, AF002005, AF002008, M64730, AF004287, U00096, AF001991, AF002003, AF001989, AF001997, AF002010, AF001996, AF001988, AF001990, AF002004, AF001992, AP009048, AF001995, AF002000
EnsemblGenome: b2733, BAE76810
KO: eco:b2733, ecj:JW2703
Nucleutide sequences
EMBL-CDS: AAD00921.1, AAC75775.1, AAD00941.1, AAD00930.1, AAD00927.1, AAD00926.1, AAD00944.1, AAA24188.1, AAD00943.1, AAD00922.1, AAD00931.1, AAD00928.1, AAD00937.1, AAD01197.1, AAD00929.1, AAD00942.1, AAD00934.1, AAD00939.1, AAD00925.1, AAD00940.1, AAD00933.1, AAD00938.1, AAD00935.1, AAD00923.1, AAD00924.1, AAD00932.1, AAA69243.1, AAD00936.1, BAE76810.1
EnsemblGenome_TRS: AAC75775, BAE76810
Protein sequencees
EnsemblGenome_PRO: BAE76810, AAC75775
RefSeq: NP_417213.1
Others
UniRef100: UniRef100_C4ZZN7
UniRef90: UniRef90_Q9S6P8
UniRef50: UniRef50_Q9S6P8

全选

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