dgt - dGTP triphosphohydrolase-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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947177 dgt

基因描述

Type	Description
Definition	dGTP triphosphohydrolase

研究结论

Date	Results	Publications
2020-03-28 10:32:00	Ec-dGTPase residues at the end of the substrate-binding pocket mimic Watson-Crick interactions providing guanine base specificity.	31019074
2015-06-20 12:44:00	The enzyme is shown to be a hexameric structure containing regulatory DNA molecules.	25694425
2012-02-25 11:28:00	our results suggest that the dgt-dependent pathway for deoxyribose-1-phosphate generation may operate under various cell conditions to provide deoxyribosyl donors.	21736641
2010-01-21 00:00:00	Data suggests that alterations of the dGTP pools as well as alterations in the level of some modified dNTP derivatives could affect the fidelity of in vivo DNA replication and, hence, account for the overall mutator effects.	18776019
2007-11-05 21:38:00	N-terminus verified by Edman degradation on mature peptide	2826481,2833745

名称对应

Type	IDs
Synonymous	ECK0159, optA
Gene	UniProtKB-ID: DGTP_ECOLI UniprotKB: P15723 UniParc: UPI0000168006 EMBL: AP009048, M31772, U70214, U00096, M29955 EnsemblGenome: BAB96737, b0160 KO: eco:b0160, ecj:JW0156
Nucleutide sequences	EMBL-CDS: AAC73271.1, BAB96737.1, AAA23716.1, AAB08590.1, AAA23679.1 EnsemblGenome_TRS: AAC73271, BAB96737
Protein sequencees	EnsemblGenome_PRO: BAB96737, AAC73271 RefSeq: NP_414702.1
Others	UniRef100: UniRef100_C4ZRQ3 UniRef90: UniRef90_Q59827 UniRef50: UniRef50_Q59827

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
31019074	The crystal structure of dGTPase reveals the molecular basis of dGTP selectivity. Proc. Natl. Acad. Sci. U.S.A. Christopher O Barnes , Ying Wu , Jinhu Song , Guowu Lin , Elizabeth L Baxter , Aaron S Brewster , V Nagarajan , Andrew Holmes , S Michael Soltis , Nicholas K Sauter , Jinwoo Ahn , Aina E Cohen , Guillermo Calero	2019-05-07	-
25694425	Structure of Escherichia coli dGTP triphosphohydrolase: a hexameric enzyme with DNA effector molecules. J Biol Chem Deepa Singh , Damian Gawel , Mark Itsko , Alejandro Hochkoeppler , Juno M Krahn , Robert E London , Roel M Schaaper	2015-04-17	-
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
21736641	The dgt gene of Escherichia coli facilitates thymine utilization in thymine-requiring strains. Mol Microbiol Mark Itsko , Roel M Schaaper	2011-09-01	-
18776019	A novel mutator of Escherichia coli carrying a defect in the dgt gene, encoding a dGTP triphosphohydrolase. J. Bacteriol. Damian Gawel , Michael D Hamilton , Roel M Schaaper	2008-11-01	dgt
16950920	Escherichia coli pfs transcription: regulation and proposed roles in autoinducer-2 synthesis and purine excretion. J. Bacteriol. Youngbae Kim , Chih M Lew , Jay D Gralla	2006-11-01	dgt, rpoS, rpoD, mtn
16397293	Escherichia coli K-12: a cooperatively developed annotation snapshot--2005. Nucleic Acids Res. Monica Riley , Takashi Abe , Martha B Arnaud , Mary K B Berlyn , Frederick R Blattner , Roy R Chaudhuri , Jeremy D Glasner , Takashi Horiuchi , Ingrid M Keseler , Takehide Kosuge , Hirotada Mori , Nicole T Perna , Guy Plunkett , Kenneth E Rudd , Margrethe H Serres , Gavin H Thomas , Nicholas R Thomson , David Wishart , Barry L Wanner	2006-01-01	pmrR, yfaS, torI, yaeP, ykfH, ykgO, ylcG, rzoD, ybdZ, cydX, gnsA, insA, ymgF, ymiA, yciX, rzoR, ynfO, yniD, yobH, yoeF, yoeB, yohO, arnE, ypdJ, ypeB, ypfN, ypjJ, arfA, yheV, ysaB, sgcB, yjhX, ytjA, yibT, yicS, yidD, yifL, ghoT, yjjZ, mntS, iroK, yifN, wecF, yigE, blr, yggP, cpxP, ygaY, hdfR, thiS, yedN, greB, rtcA, smf, ygcU, ypjK, hokE, sslE, glcF, glcE, glvC, yhaM, tdcG, ytfR, yehH, hokB, ldrD, hokA, ldrA, ldrB, ecnA, ecnB, gapC, yfjD, yhdP, yjjV, cysW, hokC, ghxQ, tatD, yjdP, cutC, nirC, frlC, aroK, gntU, yedS, dgoD, dgoA, dgoR, yigL, ldrC, ylbE, ydbJ, yeiW, yehK, yaiX, yoeA, yneM
16738553	Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Mol. Syst. Biol. Koji Hayashi , Naoki Morooka , Yoshihiro Yamamoto , Katsutoshi Fujita , Katsumi Isono , Sunju Choi , Eiichi Ohtsubo , Tomoya Baba , Barry L Wanner , Hirotada Mori , Takashi Horiuchi	2006-01-01	pmrR, torI, yaeP, ykfH, ykgO, ylcG, rzoD, ybdZ, cydX, gnsA, insA, ymgF, ymiA, yciX, rzoR, ynfO, yniD, yobH, yoeB, yohO, arnE, ypeB, ypfN, ypjJ, arfA, yheV, ysaB, sgcB, yjhX, ytjA, yibT, yicS, yidD, yifL, ghoT, yjjZ, mntS, iroK, wecF, yigE, blr, yggP, cpxP, hdfR, thiS, greB, rtcA, smf, ygcU, ypjK, hokE, sslE, glcF, glcE, yhaM, tdcG, ytfR, hokB, ldrD, hokA, ldrA, ldrB, ecnA, ecnB, yfjD, yhdP, yjjV, cysW, hokC, ghxQ, tatD, yjdP, cutC, nirC, frlC, aroK, gntU, dgoD, dgoA, dgoR, yigL, ldrC, ylbE, ydbJ, yeiW, yehK, yneM, ykfM, ylcI, yciY, yncL, ylcH, ynhF, yciZ, ydgU, ypfM, ymgI, ymgJ, dinQ
9278503	The complete genome sequence of Escherichia coli K-12. Science F R Blattner , G Plunkett , C A Bloch , N T Perna , V Burland , M Riley , J Collado-Vides , J D Glasner , C K Rode , G F Mayhew , J Gregor , N W Davis , H A Kirkpatrick , M A Goeden , D J Rose , B Mau , Y Shao	1997-09-05	-
8202364	Systematic sequencing of the Escherichia coli genome: analysis of the 2.4-4.1 min (110,917-193,643 bp) region. Nucleic Acids Res. N Fujita , H Mori , T Yura , A Ishihama	1994-05-11	-

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