dbpA - ATP-dependent RNA helicase DbpA-BMKCloudï½ç¾è¿å®¢äº

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947153 dbpA

基因描述

Type	Description
Definition	ATP-dependent RNA helicase DbpA

研究结论

Date	Results	Publications
2016-06-07 09:36:00	Overexpression of the inactive DbpA R331A mutant appears to block assembly at a late stage when the peptidyl transferase center is formed, indicating a possible role for DbpA promoting this conformational change.	19734347
2010-01-21 00:00:00	The presented analysis of the DbpA ATPase cycle reaction mechanism provides a rigorous kinetic and thermodynamic foundation for developing testable hypotheses regarding the functions and molecular mechanisms of DEAD-box helicases.	18237742
2010-01-21 00:00:00	Identification of dominant-negative mutant form of DbpA that results in a slow growth phenotype.	17986459
2010-01-21 00:00:00	results favor models where DbpA functions as an active monomer that possesses two distinct RNA binding sites, one in the helicase core domain and the other in the carboxyl-terminal domain	16325852
2010-01-21 00:00:00	The directionality of helicase activity of DbpA has been determined; DbpA is defined as a 3'-> 5' helicase.	15910005

名称对应

Type	IDs
Synonymous	ECK1340, rhlC
Gene	UniProtKB-ID: DBPA_ECOLI UniprotKB: P21693 UniParc: UPI0000128F2F EMBL: U00096, X52647, AP009048 EnsemblGenome: BAA14946, b1343 KO: eco:b1343, ecj:JW1337
Nucleutide sequences	EMBL-CDS: AAC74425.1, CAA36872.1, BAA14946.1 EnsemblGenome_TRS: BAA14946, AAC74425
Protein sequencees	EnsemblGenome_PRO: BAA14946, AAC74425 RefSeq: NP_415859.1
Others	UniRef100: UniRef100_P21693 UniRef90: UniRef90_P21693 UniRef50: UniRef50_P21693

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mRNA

Protein

UniprotKB

Description

Refseq

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Location

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Pubmed编号	文献信息	发表日期	相关基因
19734347	A dominant negative mutant of the E. coli RNA helicase DbpA blocks assembly of the 50S ribosomal subunit. Nucleic Acids Res. Lisa M Sharpe Elles , Michael T Sykes , James R Williamson , Olke C Uhlenbeck	2009-10-01	dbpA, YBX3
19393667	Unwinding by local strand separation is critical for the function of DEAD-box proteins as RNA chaperones. J Mol Biol Mark Del Campo , Sabine Mohr , Yue Jiang , Huijue Jia , Eckhard Jankowsky , Alan M Lambowitz	2009-06-19	-
18565105	Ribosome assembly in Escherichia coli strains lacking the RNA helicase DeaD/CsdA or DbpA. FEBS J. Lauri Peil , Kai VirumÃ¤e , Jaanus Remme	2008-08-01	dbpA, deaD
18237742	The ATPase cycle mechanism of the DEAD-box rRNA helicase, DbpA. J Mol Biol Arnon Henn , Wenxiang Cao , David D Hackney , Enrique M De La Cruz	2008-03-14	-
17986459	Mutation of the arginine finger in the active site of Escherichia coli DbpA abolishes ATPase and helicase activity and confers a dominant slow growth phenotype. Nucleic Acids Res Lisa M Sharpe Elles , Olke C Uhlenbeck	2008-01-01	-
16325852	Hydrodynamic characterization of the DEAD-box RNA helicase DbpA. J. Mol. Biol. Miguel A Talavera , Erin E Matthews , William K Eliason , Irit Sagi , Jimin Wang , Arnon Henn , Enrique M De La Cruz	2006-01-27	dbpA
16738553	Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Mol. Syst. Biol. Koji Hayashi , Naoki Morooka , Yoshihiro Yamamoto , Katsutoshi Fujita , Katsumi Isono , Sunju Choi , Eiichi Ohtsubo , Tomoya Baba , Barry L Wanner , Hirotada Mori , Takashi Horiuchi	2006-01-01	pmrR, torI, yaeP, ykfH, ykgO, ylcG, rzoD, ybdZ, cydX, gnsA, insA, ymgF, ymiA, yciX, rzoR, ynfO, yniD, yobH, yoeB, yohO, arnE, ypeB, ypfN, ypjJ, arfA, yheV, ysaB, sgcB, yjhX, ytjA, yibT, yicS, yidD, yifL, ghoT, yjjZ, mntS, iroK, wecF, yigE, blr, yggP, cpxP, hdfR, thiS, greB, rtcA, smf, ygcU, ypjK, hokE, sslE, glcF, glcE, yhaM, tdcG, ytfR, hokB, ldrD, hokA, ldrA, ldrB, ecnA, ecnB, yfjD, yhdP, yjjV, cysW, hokC, ghxQ, tatD, yjdP, cutC, nirC, frlC, aroK, gntU, dgoD, dgoA, dgoR, yigL, ldrC, ylbE, ydbJ, yeiW, yehK, yneM, ykfM, ylcI, yciY, yncL, ylcH, ynhF, yciZ, ydgU, ypfM, ymgI, ymgJ, dinQ
16935881	DEAD-box RNA helicases in Escherichia coli. Nucleic Acids Res. Isabelle Iost , Marc Dreyfus	2006-01-01	rhlE, srmB, dbpA, deaD, rhlB
16397293	Escherichia coli K-12: a cooperatively developed annotation snapshot--2005. Nucleic Acids Res. Monica Riley , Takashi Abe , Martha B Arnaud , Mary K B Berlyn , Frederick R Blattner , Roy R Chaudhuri , Jeremy D Glasner , Takashi Horiuchi , Ingrid M Keseler , Takehide Kosuge , Hirotada Mori , Nicole T Perna , Guy Plunkett , Kenneth E Rudd , Margrethe H Serres , Gavin H Thomas , Nicholas R Thomson , David Wishart , Barry L Wanner	2006-01-01	pmrR, yfaS, torI, yaeP, ykfH, ykgO, ylcG, rzoD, ybdZ, cydX, gnsA, insA, ymgF, ymiA, yciX, rzoR, ynfO, yniD, yobH, yoeF, yoeB, yohO, arnE, ypdJ, ypeB, ypfN, ypjJ, arfA, yheV, ysaB, sgcB, yjhX, ytjA, yibT, yicS, yidD, yifL, ghoT, yjjZ, mntS, iroK, yifN, wecF, yigE, blr, yggP, cpxP, ygaY, hdfR, thiS, yedN, greB, rtcA, smf, ygcU, ypjK, hokE, sslE, glcF, glcE, glvC, yhaM, tdcG, ytfR, yehH, hokB, ldrD, hokA, ldrA, ldrB, ecnA, ecnB, gapC, yfjD, yhdP, yjjV, cysW, hokC, ghxQ, tatD, yjdP, cutC, nirC, frlC, aroK, gntU, yedS, dgoD, dgoA, dgoR, yigL, ldrC, ylbE, ydbJ, yeiW, yehK, yaiX, yoeA, yneM
15910005	Escherichia coli DbpA is a 3' --> 5' RNA helicase. Biochemistry Camille M Diges , Olke C Uhlenbeck	2005-05-31	dbpA

研究热度

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