| Type | Description |
|---|---|
| Definition | periplasmic serine endoprotease DegP |
| Date | Results | Publications |
|---|---|---|
| 2020-06-27 12:35:00 | DegP plays a critical role in protein quality control in the bacterial periplasm by degrading both periplasmic proteins and beta-barrel outer membrane proteins under stress conditions and likely also by participating in the folding of chimeric beta-barrel outer membrane proteins. | 31738379 |
| 2020-04-04 10:30:00 | Suppressor mutations in degS overcome the acute temperature-sensitive phenotype of DeltadegP and DeltadegP Deltatol-pal mutants of Escherichia coli. | 30858298 |
| 2019-06-08 13:09:00 | demonstrate the interaction of DegP with typical cellular substrate proteins in cells during acid stress and/or recovery stages by using unnatural amino acid-mediated in vivo photo-crosslinking, as well as the degradation of periplasmic proteins by DegP during recovery after acidic denaturation | 30085413 |
| 2018-10-20 12:03:00 | Our results suggest that YjfN is a novel "suicide activator" for DegP that enhances DegP proteolysis under misfolded protein stress. | 28947671 |
| 2017-10-14 11:38:00 | Here, the authors demonstrate that a mutant variant of an outer-membrane lipoprotein, Lpp(+Leu), can function as a novel allosteric effector that changes the dynamic range of DegP activity. | 28923470 |
| Type | IDs |
|---|---|
| Synonymous | ECK0160, htrA, ptd |
| Gene |
UniProtKB-ID:
DEGP_ECOLI
UniprotKB:
P0C0V0
UniParc:
UPI0000129175
EMBL:
U00096,
U70214,
M31772,
X12457,
AP009048,
M36536,
M29955
EnsemblGenome:
b0161,
BAB96738
KO:
eco:b0161,
ecj:JW0157
|
| Nucleutide sequences |
EMBL-CDS:
CAA30997.1,
AAC73272.1,
AAA23680.1,
AAA23717.1,
AAB08591.1,
BAB96738.1,
AAA23994.1
EnsemblGenome_TRS:
AAC73272,
BAB96738
|
| Protein sequencees |
EnsemblGenome_PRO:
AAC73272,
BAB96738
RefSeq:
NP_414703.1
|
| Others |
UniRef100:
UniRef100_P0C0V1
UniRef90:
UniRef90_P0C0V1
UniRef50:
UniRef50_P39099
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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