| Type | Description |
|---|---|
| Definition | endonuclease III |
| Date | Results | Publications |
|---|---|---|
| 2017-07-29 10:06:00 | WT NTHL1 (human) and Nth (E. coli) are remarkably alike with respect to specificity of glycosylase reaction, and although NTHL1 is a much slower enzyme than Nth, the tighter binding of NTHL1 compensates, resulting in similar kcat/Kd values for both enzymes with each of the substrates tested. EcoNth Thr121 residue influences enzyme binding to DNA, as binding is significantly reduced with the Thr121Ala variant. | 28292631 |
| 2011-09-10 11:00:00 | A possible pathway is proposed through which charge can travel between the DNA and the iron sulfur cluster of EndoIII, as a first step in damage detection. | 21651304 |
| 2010-01-21 00:00:00 | Endonuclease III does not protect E.coli against possible mutations attributable to formamidopyrimidine lesions. | 15944451 |
| 2010-01-21 00:00:00 | Electrochemical measurement of endonuclease III using DNA-modified electrodes demonstrates that this base excision repair enzyme containing a [4Fe-4S] cofactor is redox-active when bound to DNA. | 15938629 |
| 2007-11-05 21:38:00 | N-terminus verified by Edman degradation on complete protein | 2669955 |
| Type | IDs |
|---|---|
| Synonymous | ECK1629 |
| Gene |
UniProtKB-ID:
END3_ECOLI
UniprotKB:
P0AB83
UniParc:
UPI0000043B83
EMBL:
AP009048,
U00096,
J02857
EnsemblGenome:
b1633,
BAA15387
KO:
ecj:JW1625,
eco:b1633
|
| Nucleutide sequences |
EMBL-CDS:
BAA15387.1,
AAC74705.1,
AAA24227.1
EnsemblGenome_TRS:
AAC74705,
BAA15387
|
| Protein sequencees |
EnsemblGenome_PRO:
BAA15387,
AAC74705
RefSeq:
NP_416150.1
|
| Others |
UniRef100:
UniRef100_P0AB84
UniRef90:
UniRef90_P0AB84
UniRef50:
UniRef50_P0AB84
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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