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947018 hmp

947018

hmp

nitric oxide dioxygenase

protein-coding

Escherichia coli str. K-12 substr. MG1655

基因描述

Type Description
Definition nitric oxide dioxygenase

研究结论

Date Results Publications
2013-09-28 10:38:00 comparison of expression of genes involved in folate metabolism and the hmp gene in strains with intact csgD gene and with deletion in csgD; expression of genes for methylene tetrahydrofolate synthesis and formyltetrahydrofolate recycling was higher in cells with CsgD than those without; expression of hmp was lower in the presence of CsgD 23824318
2010-10-23 10:23:00 This study demonstrates, for the first time, that Hmp contributes to the protection of uropathogenic Escherichia coli against nitric oxide-mediated toxicity in vitro. 20399845
2010-01-21 00:00:00 The lack of swarming motility of the hmp mutant and its aflagellate state suggest that Hmp synthesis is a metabolic burden in the absence of NO-related stresses. 17611046
2010-01-21 00:00:00 produces superoxide; during prolonged oxidation of NADH, the spectral signals of Hmp decayed and iron was released in a process prevented by superoxide dismutase or catalase 15340787
2010-01-21 00:00:00 HMP catalyzes oxidation of NO to NO(3)(-) (NO-dioxygenase activity) in vivo & in vitro in presence of O(2) & NADH. It also catalyzes reduction of several alkylhydroperoxide substrates into their corresponding alcohols using NADH as electron donor[review] 18379989

名称对应

Type IDs
Synonymous ECK2549, fsrB, hmpA
Gene
UniProtKB-ID: HMP_ECOLI
UniprotKB: P24232
UniParc: UPI0000111A1D
EMBL: U00096, AP009048, J01620, X58872
EnsemblGenome: b2552, BAA16460
KO: eco:b2552, ecj:JW2536
Nucleutide sequences
EMBL-CDS: AAA23911.1, BAA16460.1, CAA41682.1, AAC75605.1
EnsemblGenome_TRS: BAA16460, AAC75605
Protein sequencees
EnsemblGenome_PRO: AAC75605, BAA16460
RefSeq: NP_417047.1
Others
UniRef100: UniRef100_P24232
UniRef90: UniRef90_P24232
UniRef50: UniRef50_P24232

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