| Type | Description |
|---|---|
| Definition | iron-sulfur cluster insertion protein IscA |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:18:00 | Ferric uptake regulator (Fur) reversibly binds a [2Fe-2S] cluster to sense intracellular iron homeostasis in Escherichia coli. | 32928958 |
| 2015-08-22 10:30:00 | deletion of IscA/SufA may disrupt the iron delivery for iron-sulfur cluster biogenesis, therefore impeding sulfur delivery by IscS, and result in the accumulation of red IscS in E. coli cells | 25907559 |
| 2015-04-04 11:32:00 | Additional studies reveal that copper can compete with iron for the metal binding site in IscA and effectively inhibits the IscA-mediated iron-sulphur cluster assembly in Escherichia coli cells. | 24946160 |
| 2011-01-08 10:31:00 | study finds IscA essential for iron-sulfur cluster assembly in E. coli under aerobic growth conditions; results provide evidence that IscA may act as an iron chaperone for the biogenesis of iron-sulfur clusters in E. coli under aerobic conditions | 20942799 |
| 2010-01-21 00:00:00 | Results suggest that the biogenesis of the [4Fe-4S] and the [2Fe-2S] clusters may have distinct pathways and that IscA/SufA paralogues are essential for the [4Fe-4S] cluster assembly, but are dispensable for the [2Fe-2S] cluster assembly. | 19309314 |
| Type | IDs |
|---|---|
| Synonymous | ECK2525, yfhF |
| Gene |
UniProtKB-ID:
ISCA_ECOLI
UniprotKB:
P0AAC8
UniParc:
UPI000013AE93
EMBL:
AP009048,
U00096,
U01827
EnsemblGenome:
BAA16422,
b2528
KO:
ecj:JW2512,
eco:b2528
|
| Nucleutide sequences |
EMBL-CDS:
BAA16422.1,
AAC75581.1
EnsemblGenome_TRS:
BAA16422,
AAC75581
|
| Protein sequencees |
EnsemblGenome_PRO:
AAC75581,
BAA16422
RefSeq:
NP_417023.1
|
| Others |
UniRef100:
UniRef100_B7UGX4
UniRef90:
UniRef90_A7MGY0
UniRef50:
UniRef50_P44672
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员