| Type | Description |
|---|---|
| Definition | inosine 5'-monophosphate dehydrogenase |
| Date | Results | Publications |
|---|---|---|
| 2010-01-21 00:00:00 | Data show that the CRP-cyclic AMP (cAMP) complex binds to a site located over 100 bp upstream of the guaB transcription start site, where it serves to downregulate P(guaB). | 19633076 |
| 2010-01-21 00:00:00 | The CBS subdomain of IMPDH may coordinate the activities of the enzymes of purine nucleotide metabolism and is essential for maintaining the normal ATP and GTP pool sizes in E. coli. | 18312263 |
| 2010-01-21 00:00:00 | Binding of FIS to binding sites centred near positions -11, +8 and +29 relative to the guaB transcription start site results in repression of guaB promoter in vitro but not in vivo, and deletion of the fis gene increased guaB promoter activity in vivo | 18524927 |
| 2007-11-05 21:38:00 | N-terminus verified by Edman degradation on complete protein | 9298646,9600841,9629924,9740056 |
| Type | IDs |
|---|---|
| Synonymous | ECK2504, guaR |
| Gene |
UniProtKB-ID:
IMDH_ECOLI
UniprotKB:
P0ADG7
UniParc:
UPI00000480C2
EMBL:
AP009048,
U00096,
X02209,
M10101
EnsemblGenome:
BAA16395,
b2508
KO:
ecj:JW5401,
eco:b2508
|
| Nucleutide sequences |
EMBL-CDS:
AAC75561.1,
CAA26133.1,
BAA16395.2,
AAB18618.1
EnsemblGenome_TRS:
AAC75561,
BAA16395
|
| Protein sequencees |
EnsemblGenome_PRO:
BAA16395,
AAC75561
RefSeq:
NP_417003.1
|
| Others |
UniRef100:
UniRef100_P0ADG8
UniRef90:
UniRef90_P0ADG8
UniRef50:
UniRef50_Q0WD32
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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