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946955 rnhA

946955

rnhA

ribonuclease HI

protein-coding

Escherichia coli str. K-12 substr. MG1655

基因描述

Type Description
Definition ribonuclease HI

研究结论

Date Results Publications
2018-01-20 11:01:00 Data show that the catalytic domains of E. coli and human RNase H have nearly identical sequence preferences, which correlate with the efficiency of RNase H-recruiting antisense oligonucleotides. 29126318
2017-11-18 12:12:00 RNase HI recruits RnlB to RnlA through N-repeated domain for inhibiting RnlA toxicity and thus plays two contrary roles in the regulation of RnlA-RnlB system. 28085056
2017-10-07 10:05:00 The authors propose that RNase H-deficient mutants convert some R-loops into R-tracts, which progress into R-gaps and then to double-strand breaks-explaining why R-tracts do not accumulate in RNase H-deficient cells, while double-strand breaks do. 28821455
2014-11-08 10:16:00 Here, authors provide the evidence that RNase HI is an essential factor for activation of RnlA. 24308852
2010-01-21 00:00:00 crystal structure of ribonuclease HI 15644213

名称对应

Type IDs
Synonymous ECK0214, cer, dasF, herA, rnh, sdrA, sin
Gene
UniProtKB-ID: RNH_ECOLI
UniprotKB: P0A7Y4
UniParc: UPI0000112C08
EMBL: K00985, AP009048, V00337, U00096, U70214, X04027
EnsemblGenome: BAA77885, b0214
KO: eco:b0214, ecj:JW0204
Nucleutide sequences
EMBL-CDS: AAB08636.1, CAA23620.1, CAA27660.1, BAA77885.1, AAC73319.1, AAA24565.1
EnsemblGenome_TRS: BAA77885, AAC73319
Protein sequencees
EnsemblGenome_PRO: AAC73319, BAA77885
RefSeq: NP_414750.1
Others
UniRef100: UniRef100_A7ZHV1
UniRef90: UniRef90_A7ZHV1
UniRef50: UniRef50_C6DC65

全选

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研究热度

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