| Type | Description |
|---|---|
| Definition | phosphocarrier protein HPr |
| Date | Results | Publications |
|---|---|---|
| 2018-11-17 11:38:00 | Glucose preference over another phosphoenolpyruvate:sugar phosphotransferase system (PTS) sugar, mannitol, is absolutely dependent on the general PTS component HPr, but not on EIIAGlc, in E. coli. Dephosphorylated HPr accumulates during the transport of glucose and interacts with the mannitol operon regulator, MtlR, to augment its repressor activity. | 28225088 |
| 2017-09-16 11:51:00 | HPr is either phosphorylated on a histidyl residue (HPr-P) or non-phosphorylated (HPr). Data suggest HPr (the non-phosphorylated form) participates in allosteric regulation of the activities of pyruvate kinase (PykF, but not PykA), phosphofructokinase (PfkB, but not PfkA), glucosamine-6-phosphate deaminase (NagB), and adenylate kinase (Adk). | 28634232 |
| 2017-06-24 10:31:00 | Results suggest that the phosphoenolpyruvate hexose phosphotransferases PTS network serves as a global sensor of the sugar influx and also monitors the levels of several non-PTS compounds. | 27557415 |
| 2014-03-01 12:15:00 | HPr antagonizes the anti-sigma70 activity of Rsd in Escherichia coli. | 24324139 |
| 2012-10-13 11:32:00 | Data show the active site histidine of histidine phosphocarrier protein HPr, His-15, is buried within the active site cleft of IIA(Chb) formed at the interface of two adjacent subunits of the IIA(Chb) trimer. | 22593574 |
| Type | IDs |
|---|---|
| Synonymous | ECK2410, ctr, hpr |
| Gene |
UniProtKB-ID:
PTHP_ECOLI
UniprotKB:
P0AA04
UniParc:
UPI0000059AFA
EMBL:
M21451,
M10425,
U00096,
M21994,
AP009048,
J02796
EnsemblGenome:
BAA16289,
b2415
KO:
ecj:JW2408,
eco:b2415
|
| Nucleutide sequences |
EMBL-CDS:
AAC75468.1,
AAA24384.1,
AAA24438.1,
BAA16289.1,
AAA24440.1,
AAA23655.1
EnsemblGenome_TRS:
AAC75468,
BAA16289
|
| Protein sequencees |
EnsemblGenome_PRO:
AAC75468,
BAA16289
RefSeq:
NP_416910.1
|
| Others |
UniRef100:
UniRef100_P0AA06
UniRef90:
UniRef90_P0AA06
UniRef50:
UniRef50_Q9KTD6
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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