| Type | Description |
|---|---|
| Definition | DNA ligase |
| Date | Results | Publications |
|---|---|---|
| 2019-02-09 10:32:00 | Ensemble and single-molecule experiments reveal that phage Mu Gam protein binds to DNA ends, slows the progress of RecBCD exonuclease, promotes binding of NAD(+)-dependent ligase A, and stimulates ligation. | 30487222 |
| 2016-08-13 10:07:00 | Kinetic mechanism and fidelity of nick sealing by Escherichia coli LigA has been described. | 26857547 |
| 2012-09-29 11:03:00 | Here the authors show that replication without ligase kills after a short resistance period. | 22582878 |
| 2010-01-21 00:00:00 | 2.3 A crystal structure of LigA bound to an adenylylated nick, which captures LigA in a state poised for strand closure and reveals the basis for nick recognition | 17466627 |
| 2010-01-21 00:00:00 | structure-function analysis of the OB, HhH & BRCT domains of LigA; study found that the BRCT domain is required in its entirety for effective nick sealing and AMP-dependent supercoil relaxation | 18515356 |
| Type | IDs |
|---|---|
| Synonymous | ECK2406, dnaL, lig, lop, pdeC |
| Gene |
UniProtKB-ID:
DNLJ_ECOLI
UniprotKB:
P15042
UniParc:
UPI000012967F
EMBL:
U00096,
M30255,
M24278,
AP009048,
U74650
EnsemblGenome:
BAA16282,
b2411
KO:
ecj:JW2403,
eco:b2411
|
| Nucleutide sequences |
EMBL-CDS:
BAA16282.2,
AAB42062.1,
AAA24071.1,
AAC75464.1,
AAA24070.1
EnsemblGenome_TRS:
AAC75464,
BAA16282
|
| Protein sequencees |
EnsemblGenome_PRO:
BAA16282,
AAC75464
RefSeq:
NP_416906.1
|
| Others |
UniRef100:
UniRef100_B1XA82
UniRef90:
UniRef90_Q8XBL5
UniRef50:
UniRef50_Q8XBL5
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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