| Type | Description |
|---|---|
| Definition | 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase |
| Date | Results | Publications |
|---|---|---|
| 2014-10-11 10:50:00 | The open-to-closed conformational transition involves movement of half the alpha-helical cap, which causes changes in the alpha/beta-domain and forces the side chain of the triad histidine to adopt a disfavored gauche conformation to form the functional triad. | 24737327 |
| 2013-12-28 10:49:00 | EcMenH has the predicted alpha/beta hydrolase fold with its core alpha/beta domain capped by helical lid. Active site, a long groove beneath the cap, contains a number of conserved basic residues and is found to bind exogeneous anions, modeled as sulfate and chloride | 23637813 |
| Type | IDs |
|---|---|
| Synonymous | ECK2257, yfbB |
| Gene |
UniProtKB-ID:
MENH_ECOLI
UniprotKB:
P37355
UniParc:
UPI000013ADD0
EMBL:
U00096,
L35030,
AP009048,
M93421
EnsemblGenome:
b2263,
BAA16087
KO:
ecj:JW2258,
eco:b2263
|
| Nucleutide sequences |
EMBL-CDS:
AAC75323.1,
AAA24151.1,
BAA16087.2
EnsemblGenome_TRS:
AAC75323,
BAA16087
|
| Protein sequencees |
EnsemblGenome_PRO:
BAA16087,
AAC75323
RefSeq:
NP_416766.1
|
| Others |
UniRef100:
UniRef100_C4ZUA6
UniRef90:
UniRef90_Q8XDX9
UniRef50:
UniRef50_Q8ZNE9
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 24737327 |
Molecular basis of the general base catalysis of an α/β-hydrolase catalytic triad. J Biol Chem Yueru Sun , Shuhui Yin , Yitao Feng , Jie Li , Jiahai Zhou , Changdong Liu , Guang Zhu , Zhihong Guo |
2014-05-30 | - |
| 24561554 |
The binary protein-protein interaction landscape of Escherichia coli. Nat. Biotechnol. Seesandra V Rajagopala , Patricia Sikorski , Ashwani Kumar , Roberto Mosca , James Vlasblom , Roland Arnold , Jonathan Franca-Koh , Suman B Pakala , Sadhna Phanse , Arnaud Ceol , Roman Häuser , Gabriella Siszler , Stefan Wuchty , Andrew Emili , Mohan Babu , Patrick Aloy , Rembert Pieper , Peter Uetz |
2014-03-01 | - |
| 23637813 |
Crystal structures of E. coli native MenH and two active site mutants. PLoS ONE Jodie M Johnston , Ming Jiang , Zhihong Guo , Edward N Baker |
2013-01-01 | - |
| 19545176 |
Biochemistry Ming Jiang , Xiaolei Chen , Xian-Hui Wu , Minjiao Chen , Yun-Dong Wu , Zhihong Guo |
2009-07-28 |
menH
|
| 18284213 |
Biochemistry Ming Jiang , Xiaolei Chen , Zu-Feng Guo , Yang Cao , Minjiao Chen , Zhihong Guo |
2008-03-18 |
menD,
menH,
ubiE
|
| 17760421 |
Biochemistry Ming Jiang , Yang Cao , Zu-Feng Guo , Minjiao Chen , Xiaolei Chen , Zhihong Guo |
2007-09-25 |
menD,
menH
|
| 16738553 |
Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Mol. Syst. Biol. Koji Hayashi , Naoki Morooka , Yoshihiro Yamamoto , Katsutoshi Fujita , Katsumi Isono , Sunju Choi , Eiichi Ohtsubo , Tomoya Baba , Barry L Wanner , Hirotada Mori , Takashi Horiuchi |
2006-01-01 |
pmrR,
torI,
yaeP,
ykfH,
ykgO,
ylcG,
rzoD,
ybdZ,
cydX,
gnsA,
insA,
ymgF,
ymiA,
yciX,
rzoR,
ynfO,
yniD,
yobH,
yoeB,
yohO,
arnE,
ypeB,
ypfN,
ypjJ,
arfA,
yheV,
ysaB,
sgcB,
yjhX,
ytjA,
yibT,
yicS,
yidD,
yifL,
ghoT,
yjjZ,
mntS,
iroK,
wecF,
yigE,
blr,
yggP,
cpxP,
hdfR,
thiS,
greB,
rtcA,
smf,
ygcU,
ypjK,
hokE,
sslE,
glcF,
glcE,
yhaM,
tdcG,
ytfR,
hokB,
ldrD,
hokA,
ldrA,
ldrB,
ecnA,
ecnB,
yfjD,
yhdP,
yjjV,
cysW,
hokC,
ghxQ,
tatD,
yjdP,
cutC,
nirC,
frlC,
aroK,
gntU,
dgoD,
dgoA,
dgoR,
yigL,
ldrC,
ylbE,
ydbJ,
yeiW,
yehK,
yneM,
ykfM,
ylcI,
yciY,
yncL,
ylcH,
ynhF,
yciZ,
ydgU,
ypfM,
ymgI,
ymgJ,
dinQ
|
| 16397293 |
Escherichia coli K-12: a cooperatively developed annotation snapshot--2005. Nucleic Acids Res. Monica Riley , Takashi Abe , Martha B Arnaud , Mary K B Berlyn , Frederick R Blattner , Roy R Chaudhuri , Jeremy D Glasner , Takashi Horiuchi , Ingrid M Keseler , Takehide Kosuge , Hirotada Mori , Nicole T Perna , Guy Plunkett , Kenneth E Rudd , Margrethe H Serres , Gavin H Thomas , Nicholas R Thomson , David Wishart , Barry L Wanner |
2006-01-01 |
pmrR,
yfaS,
torI,
yaeP,
ykfH,
ykgO,
ylcG,
rzoD,
ybdZ,
cydX,
gnsA,
insA,
ymgF,
ymiA,
yciX,
rzoR,
ynfO,
yniD,
yobH,
yoeF,
yoeB,
yohO,
arnE,
ypdJ,
ypeB,
ypfN,
ypjJ,
arfA,
yheV,
ysaB,
sgcB,
yjhX,
ytjA,
yibT,
yicS,
yidD,
yifL,
ghoT,
yjjZ,
mntS,
iroK,
yifN,
wecF,
yigE,
blr,
yggP,
cpxP,
ygaY,
hdfR,
thiS,
yedN,
greB,
rtcA,
smf,
ygcU,
ypjK,
hokE,
sslE,
glcF,
glcE,
glvC,
yhaM,
tdcG,
ytfR,
yehH,
hokB,
ldrD,
hokA,
ldrA,
ldrB,
ecnA,
ecnB,
gapC,
yfjD,
yhdP,
yjjV,
cysW,
hokC,
ghxQ,
tatD,
yjdP,
cutC,
nirC,
frlC,
aroK,
gntU,
yedS,
dgoD,
dgoA,
dgoR,
yigL,
ldrC,
ylbE,
ydbJ,
yeiW,
yehK,
yaiX,
yoeA,
yneM
|
| 16381862 |
MEROPS: the peptidase database. Nucleic Acids Res. Neil D Rawlings , Fraser R Morton , Alan J Barrett |
2006-01-01 |
yghX,
lspA,
rseP,
yafL,
yafJ,
mhpC,
hypF,
yahJ,
frmB,
codA,
pepD,
yfhR,
yajL,
clpP,
lon,
trpD,
allB,
allC,
loiP,
ompT,
mepH,
dacA,
asnB,
ybfF,
nagA,
dacC,
iaaA,
ddpX,
ycaL,
ycbK,
ycbZ,
hyaD,
cohE,
abgA,
umuD,
ldcA,
pyrC,
yfbL,
sohB,
puuD,
abgB,
mpaA,
ynbC,
ycjY,
ydcP,
pqqL,
htpX,
dcp,
prc,
pyrG,
nlpC,
sppA,
tsaB,
pepT,
ptrB,
mepM,
ydgD,
hchA,
dacD,
rutD,
yegQ,
pbpG,
mepS,
menH,
elaD,
purF,
mepA,
ypdE,
ypdF,
ampH,
yfeW,
nlpD,
bepA,
lepB,
degP,
iap,
pepN,
ptrA,
guaA,
ygeR,
hyuA,
ygeY,
guaD,
pepP,
hycI,
pppA,
aes,
tsaD,
agaA,
yhbO,
ftsH,
dacB,
gltB,
tldD,
degQ,
gspO,
yheT,
degS,
pabA
|
| 15911532 |
Mol Cell Proteomics Ana Lopez-Campistrous , Paul Semchuk , Lorne Burke , Taunja Palmer-Stone , Stephen J Brokx , Gordon Broderick , Drell Bottorff , Sandra Bolch , Joel H Weiner , Michael J Ellison |
2005-08-01 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员