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946704 glpT

946704

glpT

sn-glycerol 3-phosphate:phosphate antiporter

protein-coding

Escherichia coli str. K-12 substr. MG1655

基因描述

Type Description
Definition sn-glycerol 3-phosphate:phosphate antiporter

研究结论

Date Results Publications
2016-06-28 10:13:00 Elevated expression of GlpT and UhpT via FNR activation contributes to increased fosfomycin susceptibility in Escherichia coli under anaerobic conditions. 26248376
2013-12-21 11:42:00 Data indicate that mutating noninteracting residues to alanine have no effect on the pulling force of C-terminal transmembrane helices (TMHs) in membrane transport proteins CaiT, BtuC, NhaA, EmrD and GlpT. 23959879
2010-01-21 00:00:00 Here we report the 3.3 A resolution structure of GlpT, the glycerol-3-phosphate transporter from the E. coli inner membrane, in the absence of a substrate and propose that GlpT operates via a single binding-site, alternating-access mechanism. 16157640
2010-01-21 00:00:00 studies suggest that only a few amino acid residues that line the GlpT transporter lumen act as specificity determinants 19720022
2010-01-21 00:00:00 simulations highlight the cavity-lining helices as being significantly flexible, suggesting that the transport mechanism may involve intra-helix motions in addition to pseudo-rigid body motions of the N- and C-terminal domains relative to one another 19037818

名称对应

Type IDs
Synonymous ECK2232
Gene
UniProtKB-ID: GLPT_ECOLI
UniprotKB: P08194
UniParc: UPI000012B7B5
EMBL: AP009048, U00096, Y00536
EnsemblGenome: b2240, BAA16059
KO: ecj:JW2234, eco:b2240
Nucleutide sequences
EMBL-CDS: BAA16059.1, CAA68598.1, AAC75300.1
EnsemblGenome_TRS: AAC75300, BAA16059
Protein sequencees
EnsemblGenome_PRO: BAA16059, AAC75300
RefSeq: NP_416743.1
Others
UniRef100: UniRef100_P08194
UniRef90: UniRef90_P08194
UniRef50: UniRef50_P08194

全选

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研究热度

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