| Type | Description |
|---|---|
| Definition | DNA gyrase subunit A |
| Date | Results | Publications |
|---|---|---|
| 2020-03-21 10:36:00 | Our findings indicate that the catalytic cycle of E. coli gyrase operates at high thermodynamic efficiency, and that the stability of DNA wrapping by the CTD provides one limit to DNA supercoil introduction, beyond which strand passage competes with ATP-dependent supercoil relaxation | 31950157 |
| 2019-11-02 13:13:00 | Inhibition of the gyrA promoter by transcription-coupled DNA supercoiling in Escherichia coli has been demonstrated. | 30282997 |
| 2019-09-21 11:34:00 | The gyrA mutations were identified in nucleotide positions 248, 255, 259, 260, 261, 273 and 300, and mutations at positions 248 and 259 resulting in amino acid changes at positions 83 and 87 were associated with quinolone resistance. | 29767711 |
| 2019-09-21 11:07:00 | High frequency of aac(6')-Ib-cr gene associated with double mutations in gyrA and parC is related to fluoroquinolone resistance | 29307860 |
| 2019-08-31 13:13:00 | Measuring the dwell time of gyrase bound to DNA revealed that most gyrase remain immobile for approximately 2 s, whereas enzymes in the vicinity of the replisome had a approximately 8 s dwell time, suggesting that when an excessive (+) supercoiling is present due to the fast progression of the fork, gyrase performs multiple rounds of catalysis without dissociating from DNA. | 30445553 |
| Type | IDs |
|---|---|
| Synonymous | ECK2223, hisW, nalA, nfxA, norA, parD |
| Gene |
UniProtKB-ID:
GYRA_ECOLI
UniprotKB:
P0AES4
UniParc:
UPI000012BE82
EMBL:
AP009048,
U00096,
X06373,
Y00544,
X06744,
M15631
EnsemblGenome:
b2231,
BAA16048
KO:
ecj:JW2225,
eco:b2231
|
| Nucleutide sequences |
EMBL-CDS:
CAA29919.1,
AAC75291.1,
AAA23948.1,
BAA16048.1,
CAA29676.1,
CAA68611.1
EnsemblGenome_TRS:
AAC75291,
BAA16048
|
| Protein sequencees |
EnsemblGenome_PRO:
BAA16048,
AAC75291
RefSeq:
NP_416734.1
|
| Others |
UniRef100:
UniRef100_P0AES4
UniRef90:
UniRef90_P0AES4
UniRef50:
UniRef50_P0AES4
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
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