cbtA - CP4-44 prophage; cytoskeleton-binding toxin CbtA-BMKCloudï½ç¾è¿å®¢äº

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946534 cbtA

基因描述

Type	Description
Definition	CP4-44 prophage; cytoskeleton-binding toxin CbtA

研究结论

Date	Results	Publications
2017-10-14 11:38:00	Although several other protein modulators are known to target FtsZ, the CbtA-interacting surface we identify represents a novel inhibitory target. Our findings establish CbtA as a dual function toxin that inhibits both cell division and cell elongation via direct and independent interactions with FtsZ and MreB.	28931012
2011-04-09 11:05:00	The authors show that YeeV toxin inhibits cell division, leads to a change in morphology and lysis of Escherichia coli cells via interaction with two essential cytoskeleton proteins, FtsZ and MreB.	21166897

名称对应

Type	IDs
Synonymous	ECK1998, yeeV
Gene	UniProtKB-ID: CBTA_ECOLI UniprotKB: P64524 UniParc: UPI000013AC1E EMBL: U00096, AP009048 EnsemblGenome: b2005, BAE76565 KO: ecj:JW1987, eco:b2005
Nucleutide sequences	EMBL-CDS: BAE76565.1, AAC75066.1 EnsemblGenome_TRS: BAE76565, AAC75066
Protein sequencees	EnsemblGenome_PRO: AAC75066, BAE76565 RefSeq: NP_416509.1
Others	UniRef100: UniRef100_P64525 UniRef90: UniRef90_P64525 UniRef50: UniRef50_P64525

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mRNA

Protein

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Pubmed编号	文献信息	发表日期	相关基因
28931012	CbtA toxin of Escherichia coli inhibits cell division and cell elongation via direct and independent interactions with FtsZ and MreB. PLoS Genet Danielle M Heller , Mrinalini Tavag , Ann Hochschild	2017-09-01	-
21166897	YeeV is an Escherichia coli toxin that inhibits cell division by targeting the cytoskeleton proteins, FtsZ and MreB. Mol Microbiol Qian Tan , Naoki Awano , Masayori Inouye	2011-01-01	-
16738553	Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Mol. Syst. Biol. Koji Hayashi , Naoki Morooka , Yoshihiro Yamamoto , Katsutoshi Fujita , Katsumi Isono , Sunju Choi , Eiichi Ohtsubo , Tomoya Baba , Barry L Wanner , Hirotada Mori , Takashi Horiuchi	2006-01-01	pmrR, torI, yaeP, ykfH, ykgO, ylcG, rzoD, ybdZ, cydX, gnsA, insA, ymgF, ymiA, yciX, rzoR, ynfO, yniD, yobH, yoeB, yohO, arnE, ypeB, ypfN, ypjJ, arfA, yheV, ysaB, sgcB, yjhX, ytjA, yibT, yicS, yidD, yifL, ghoT, yjjZ, mntS, iroK, wecF, yigE, blr, yggP, cpxP, hdfR, thiS, greB, rtcA, smf, ygcU, ypjK, hokE, sslE, glcF, glcE, yhaM, tdcG, ytfR, hokB, ldrD, hokA, ldrA, ldrB, ecnA, ecnB, yfjD, yhdP, yjjV, cysW, hokC, ghxQ, tatD, yjdP, cutC, nirC, frlC, aroK, gntU, dgoD, dgoA, dgoR, yigL, ldrC, ylbE, ydbJ, yeiW, yehK, yneM, ykfM, ylcI, yciY, yncL, ylcH, ynhF, yciZ, ydgU, ypfM, ymgI, ymgJ, dinQ
16397293	Escherichia coli K-12: a cooperatively developed annotation snapshot--2005. Nucleic Acids Res. Monica Riley , Takashi Abe , Martha B Arnaud , Mary K B Berlyn , Frederick R Blattner , Roy R Chaudhuri , Jeremy D Glasner , Takashi Horiuchi , Ingrid M Keseler , Takehide Kosuge , Hirotada Mori , Nicole T Perna , Guy Plunkett , Kenneth E Rudd , Margrethe H Serres , Gavin H Thomas , Nicholas R Thomson , David Wishart , Barry L Wanner	2006-01-01	pmrR, yfaS, torI, yaeP, ykfH, ykgO, ylcG, rzoD, ybdZ, cydX, gnsA, insA, ymgF, ymiA, yciX, rzoR, ynfO, yniD, yobH, yoeF, yoeB, yohO, arnE, ypdJ, ypeB, ypfN, ypjJ, arfA, yheV, ysaB, sgcB, yjhX, ytjA, yibT, yicS, yidD, yifL, ghoT, yjjZ, mntS, iroK, yifN, wecF, yigE, blr, yggP, cpxP, ygaY, hdfR, thiS, yedN, greB, rtcA, smf, ygcU, ypjK, hokE, sslE, glcF, glcE, glvC, yhaM, tdcG, ytfR, yehH, hokB, ldrD, hokA, ldrA, ldrB, ecnA, ecnB, gapC, yfjD, yhdP, yjjV, cysW, hokC, ghxQ, tatD, yjdP, cutC, nirC, frlC, aroK, gntU, yedS, dgoD, dgoA, dgoR, yigL, ldrC, ylbE, ydbJ, yeiW, yehK, yaiX, yoeA, yneM
14594833	A novel family of Escherichia coli toxin-antitoxin gene pairs. J Bacteriol Jason M Brown , Karen Joy Shaw	2003-11-01	-
12886937	Prophages and bacterial genomics: what have we learned so far? Mol. Microbiol. Sherwood Casjens	2003-07-01	-
9278503	The complete genome sequence of Escherichia coli K-12. Science F R Blattner , G Plunkett , C A Bloch , N T Perna , V Burland , M Riley , J Collado-Vides , J D Glasner , C K Rode , G F Mayhew , J Gregor , N W Davis , H A Kirkpatrick , M A Goeden , D J Rose , B Mau , Y Shao	1997-09-05	-

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