| Type | Description |
|---|---|
| Definition | protein interacting with PRKCA 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-02-22 10:37:00 | Arf1, AP1, and PICK1 are key coordinators of actin polymerization. | 31740529 |
| 2019-05-18 12:20:00 | PICK1 plays a pivotal role in sepsis-induced acute lung injury by regulating glutathione synthesis via affecting the substrate-specific subunit of lung cystine/glutamate transporter, xCT | 29471107 |
| 2019-04-13 10:47:00 | Study has demonstrated that ARX is a novel substrate of PRKCA, with phosphorylation at serine 174, and that the c-terminal region of ARX required to bind PICK1. Binding causes a shift in PICK1 subcellular localization to the nucleus to co-locate with the ARX protein, and truncation of this C-terminal region leads to the same loss of transcriptional activation as S174A mutant. | 30419043 |
| 2018-12-22 11:26:00 | this is the first study to indicate that PICK1 polymorphisms may associate with cognitive functions in schizophrenic patients. | 28507309 |
| 2018-12-22 10:19:00 | Coincident with the loss of PICK1 by GBF1-activated ARF1, CDC42 recruitment leads to the activation of IRSp53 and the complex, resulting in a burst of F-actin polymerisation potentially powering scission. | 29743604 |
| Type | IDs |
|---|---|
| Synonymous | PICK, PRKCABP |
| Gene |
UniProtKB-ID:
PICK1_HUMAN,
A0A024R1J5_HUMAN
UniprotKB:
Q9NRD5,
A0A024R1J5
UniParc:
UPI0000131A98,
UPI00003E298D
EMBL:
CH471095,
AL049654,
CR456550,
AF231710,
AK092818,
BC017561,
AB026491,
AL031587
Ensembl:
ENSG00000100151
KO:
hsa:9463
|
| Nucleutide sequences |
EMBL-CDS:
AAF97502.1,
BAG52614.1,
EAW60208.1,
CAB41082.1,
AAH17561.1,
CAG30436.1,
BAA89294.1,
EAW60210.1,
EAW60211.1,
EAW60207.1,
EAW60212.1
Gene_ORFName:
hCG_41846
Ensembl_TRS:
ENST00000356976,
ENST00000404072
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000349465,
ENSP00000385205
RefSeq:
XP_011528819.1,
NP_001034672.1,
XP_006724443.1,
NP_001034673.1,
XP_016884579.1,
XP_016884583.1,
XP_016884581.1,
XP_006724442.1,
XP_016884582.1,
NP_036539.1,
XP_016884580.1
|
| Others |
UniRef100:
UniRef100_Q9NRD5
UniRef90:
UniRef90_Q9NRD5
UniRef50:
UniRef50_Q9NRD5
UniGene:
Hs.180871
CCDS:
CCDS13965.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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