Type | Description |
---|---|
Definition | fumarase C |
Date | Results | Publications |
---|---|---|
2020-07-25 10:57:00 | we report structural and kinetic analyses from Escherichia coli FumC variants to understand the contribution of SS Loop residues S318, K324, and N326. High-resolution X-ray crystallographic results reveal three distinct FumC active-site conformations; disordered-open, ordered-open, and the newly discovered ordered-closed. | 31514245 |
2014-02-22 13:04:00 | Starting with an exclusively mitochondrial targeted FumC (attached to a strong MTS), we show that two randomly acquired mutations within the prokaryotic FumC sequence are sufficient to cause substantial dual targeting by reverse translocation | 23462316 |
2012-11-03 10:08:00 | The results show that Crp is an activator of fumA and fumC gene expression under various oxygen conditions and growth rates. | 22752906 |
2010-01-21 00:00:00 | water is a permanent member of the active site of FumC, which uses an imidazole-imidazolium conversion to control access at the allosteric B site | 16204892 |
2007-11-05 21:38:00 | N-terminus verified by Edman degradation on complete protein | 1917897,8496960 |
Type | IDs |
---|---|
Synonymous | ECK1606 |
Gene |
UniProtKB-ID:
FUMC_ECOLI
UniprotKB:
P05042
UniParc:
UPI00001117A0
EMBL:
U00096,
X00522,
AP009048,
X04065
EnsemblGenome:
b1611,
BAA15349
KO:
ecj:JW1603,
eco:b1611
|
Nucleutide sequences |
EMBL-CDS:
CAA25205.1,
AAC74683.1,
BAA15349.1,
CAA27698.1
EnsemblGenome_TRS:
AAC74683,
BAA15349
|
Protein sequencees |
EnsemblGenome_PRO:
BAA15349,
AAC74683
RefSeq:
NP_416128.1
|
Others |
UniRef100:
UniRef100_P05042
UniRef90:
UniRef90_P05042
UniRef50:
UniRef50_P05042
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
---|---|---|---|
31514245 |
Closed fumarase C active-site structures reveal SS Loop residue contribution in catalysis. FEBS Lett. Gage M Stuttgen , Julian D Grosskopf , Colton R Berger , John F May , Basudeb Bhattacharyya , Todd M Weaver |
2020-01-01 | - |
23462316 |
Evolving dual targeting of a prokaryotic protein in yeast. Mol. Biol. Evol. Efrat Burak , Ohad Yogev , Shimon Sheffer , Ora Schueler-Furman , Ophry Pines |
2013-07-01 |
fumC
|
22752906 |
Regulatory role of cAMP receptor protein over Escherichia coli fumarase genes. J. Microbiol. Yu-Pei Chen , Hsiao-Hsien Lin , Chi-Dung Yang , Shin-Hong Huang , Ching-Ping Tseng |
2012-06-01 |
fumC,
fumA,
crp
|
21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
19383690 |
Tellurite-mediated disabling of [4Fe-4S] clusters of Escherichia coli dehydratases. Microbiology (Reading, Engl.) Iván L Calderón , Alex O ElÃas , Eugenia L Fuentes , Gonzalo A Pradenas , Miguel E Castro , Felipe A Arenas , José M Pérez , Claudio C Vásquez |
2009-06-01 |
acnB,
fumC,
acnA,
fumA
|
18213409 |
Mol Biosyst Mahbuba Rahman , Kazuyuki Shimizu |
2008-02-01 |
acnB,
tktB,
fumC,
talA,
rpoS
|
17379704 |
Microbiology (Reading, Engl.) Erlend Bore , Michel Hébraud , Ingrid Chafsey , Christophe Chambon , Camilla Skjæret , Birgitte Moen , Trond Møretrø , Ãyvind Langsrud , Knut Rudi , Solveig Langsrud |
2007-04-01 | - |
17222132 |
Temporal gene-expression in Escherichia coli K-12 biofilms. Environ. Microbiol. Joanna Domka , Jintae Lee , Tarun Bansal , Thomas K Wood |
2007-02-01 |
gatR,
cpxP,
yedN,
cysW,
ygaQ,
yfjI,
yaaW,
aceK,
ais,
ompX,
prpR,
tauD,
tauA,
ymgC,
tfaD,
ybcV,
stfR,
citC,
citA,
sucA,
sdhC,
ariR,
sdhA,
citD,
aspC,
hyaD,
hyaA,
hyaC,
cbdA,
bluR,
narG,
prpD,
ydeM,
adhP,
ydeQ,
eamA,
fumC,
glsA,
torC,
astC,
astE,
astD,
astA,
torT,
wcaD,
gatC,
gatB,
gatZ,
yafU,
ykfI,
cysU,
cysP,
hyfG,
grcA,
ypjF,
cysN,
cysH,
cysI,
cysJ,
hyfC,
kbaY,
agaC,
agaB,
acrS,
yhcA,
acrF,
gadE,
hdeD,
hdeB,
gadA,
gadW,
dctA,
gyrB,
phoU,
aceA,
frdA,
mpl,
iraD,
ymgA,
ykfA
|
16738553 |
Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Mol. Syst. Biol. Koji Hayashi , Naoki Morooka , Yoshihiro Yamamoto , Katsutoshi Fujita , Katsumi Isono , Sunju Choi , Eiichi Ohtsubo , Tomoya Baba , Barry L Wanner , Hirotada Mori , Takashi Horiuchi |
2006-01-01 |
pmrR,
torI,
yaeP,
ykfH,
ykgO,
ylcG,
rzoD,
ybdZ,
cydX,
gnsA,
insA,
ymgF,
ymiA,
yciX,
rzoR,
ynfO,
yniD,
yobH,
yoeB,
yohO,
arnE,
ypeB,
ypfN,
ypjJ,
arfA,
yheV,
ysaB,
sgcB,
yjhX,
ytjA,
yibT,
yicS,
yidD,
yifL,
ghoT,
yjjZ,
mntS,
iroK,
wecF,
yigE,
blr,
yggP,
cpxP,
hdfR,
thiS,
greB,
rtcA,
smf,
ygcU,
ypjK,
hokE,
sslE,
glcF,
glcE,
yhaM,
tdcG,
ytfR,
hokB,
ldrD,
hokA,
ldrA,
ldrB,
ecnA,
ecnB,
yfjD,
yhdP,
yjjV,
cysW,
hokC,
ghxQ,
tatD,
yjdP,
cutC,
nirC,
frlC,
aroK,
gntU,
dgoD,
dgoA,
dgoR,
yigL,
ldrC,
ylbE,
ydbJ,
yeiW,
yehK,
yneM,
ykfM,
ylcI,
yciY,
yncL,
ylcH,
ynhF,
yciZ,
ydgU,
ypfM,
ymgI,
ymgJ,
dinQ
|
16397293 |
Escherichia coli K-12: a cooperatively developed annotation snapshot--2005. Nucleic Acids Res. Monica Riley , Takashi Abe , Martha B Arnaud , Mary K B Berlyn , Frederick R Blattner , Roy R Chaudhuri , Jeremy D Glasner , Takashi Horiuchi , Ingrid M Keseler , Takehide Kosuge , Hirotada Mori , Nicole T Perna , Guy Plunkett , Kenneth E Rudd , Margrethe H Serres , Gavin H Thomas , Nicholas R Thomson , David Wishart , Barry L Wanner |
2006-01-01 |
pmrR,
yfaS,
torI,
yaeP,
ykfH,
ykgO,
ylcG,
rzoD,
ybdZ,
cydX,
gnsA,
insA,
ymgF,
ymiA,
yciX,
rzoR,
ynfO,
yniD,
yobH,
yoeF,
yoeB,
yohO,
arnE,
ypdJ,
ypeB,
ypfN,
ypjJ,
arfA,
yheV,
ysaB,
sgcB,
yjhX,
ytjA,
yibT,
yicS,
yidD,
yifL,
ghoT,
yjjZ,
mntS,
iroK,
yifN,
wecF,
yigE,
blr,
yggP,
cpxP,
ygaY,
hdfR,
thiS,
yedN,
greB,
rtcA,
smf,
ygcU,
ypjK,
hokE,
sslE,
glcF,
glcE,
glvC,
yhaM,
tdcG,
ytfR,
yehH,
hokB,
ldrD,
hokA,
ldrA,
ldrB,
ecnA,
ecnB,
gapC,
yfjD,
yhdP,
yjjV,
cysW,
hokC,
ghxQ,
tatD,
yjdP,
cutC,
nirC,
frlC,
aroK,
gntU,
yedS,
dgoD,
dgoA,
dgoR,
yigL,
ldrC,
ylbE,
ydbJ,
yeiW,
yehK,
yaiX,
yoeA,
yneM
|
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