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946147 fumC

946147

fumC

fumarase C

protein-coding

Escherichia coli str. K-12 substr. MG1655

基因描述

Type Description
Definition fumarase C

研究结论

Date Results Publications
2020-07-25 10:57:00 we report structural and kinetic analyses from Escherichia coli FumC variants to understand the contribution of SS Loop residues S318, K324, and N326. High-resolution X-ray crystallographic results reveal three distinct FumC active-site conformations; disordered-open, ordered-open, and the newly discovered ordered-closed. 31514245
2014-02-22 13:04:00 Starting with an exclusively mitochondrial targeted FumC (attached to a strong MTS), we show that two randomly acquired mutations within the prokaryotic FumC sequence are sufficient to cause substantial dual targeting by reverse translocation 23462316
2012-11-03 10:08:00 The results show that Crp is an activator of fumA and fumC gene expression under various oxygen conditions and growth rates. 22752906
2010-01-21 00:00:00 water is a permanent member of the active site of FumC, which uses an imidazole-imidazolium conversion to control access at the allosteric B site 16204892
2007-11-05 21:38:00 N-terminus verified by Edman degradation on complete protein 1917897,8496960

名称对应

Type IDs
Synonymous ECK1606
Gene
UniProtKB-ID: FUMC_ECOLI
UniprotKB: P05042
UniParc: UPI00001117A0
EMBL: U00096, X00522, AP009048, X04065
EnsemblGenome: b1611, BAA15349
KO: ecj:JW1603, eco:b1611
Nucleutide sequences
EMBL-CDS: CAA25205.1, AAC74683.1, BAA15349.1, CAA27698.1
EnsemblGenome_TRS: AAC74683, BAA15349
Protein sequencees
EnsemblGenome_PRO: BAA15349, AAC74683
RefSeq: NP_416128.1
Others
UniRef100: UniRef100_P05042
UniRef90: UniRef90_P05042
UniRef50: UniRef50_P05042

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