| Type | Description |
|---|---|
| Definition | DNA topoisomerase III |
| Date | Results | Publications |
|---|---|---|
| 2021-02-06 13:52:00 | Supercoiling, R-loops, Replication and the Functions of Bacterial Type 1A Topoisomerases. | 32120891 |
| 2019-01-19 11:12:00 | Study finding that both E. coli topo I and III control R-loop formation/accumulation, mostly to inhibit unregulated replication, may suggest that R-loops have been a problem early in the evolution of life. Furthermore, data show that E. coli cells can survive in the absence of type 1A topos, owing to the surproduction of topo IV that can relax excess negative supercoiling and prevent R-loop formation. | 30222737 |
| 2014-02-01 10:35:00 | These results suggest that topoisomerase III participates in orderly and efficient chromosome segregation in E. coli. | 23066834 |
| 2013-06-29 12:08:00 | Topo III unlinking rates were linearly related to the DNA collision frequency. | 23460205 |
| 2013-01-26 11:15:00 | Topoisomerase III relaxes DNA efficiently in fast processive runs, but with long pauses before relaxation runs. | 22923519 |
| Type | IDs |
|---|---|
| Synonymous | ECK1761, mutR |
| Gene |
UniProtKB-ID:
TOP3_ECOLI
UniprotKB:
P14294
UniParc:
UPI0000137166
EMBL:
J05076,
AP009048,
U00096
EnsemblGenome:
BAA15551,
b1763
KO:
eco:b1763,
ecj:JW1752
|
| Nucleutide sequences |
EMBL-CDS:
AAA83923.1,
BAA15551.1,
AAC74833.1
EnsemblGenome_TRS:
AAC74833,
BAA15551
|
| Protein sequencees |
EnsemblGenome_PRO:
BAA15551,
AAC74833
RefSeq:
NP_416277.1
|
| Others |
UniRef100:
UniRef100_P14294
UniRef90:
UniRef90_P14294
UniRef50:
UniRef50_P14294
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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