| Type | Description |
|---|---|
| Definition | Cu(+) exporting P-type ATPase;soluble Cu(+) chaperone |
| Date | Results | Publications |
|---|---|---|
| 2017-10-07 11:22:00 | CopA chaperone is expressed in E. coli from the same gene that encodes the transporter. Some ribosomes translating copA undergo programmed frameshifting, terminate translation in the -1 frame, and generate the 70 aa-long polypeptide CopA(Z), which helps cells survive toxic copper concentrations. The high efficiency of frameshifting is achieved by the combined stimulatory action of a "slippery" sequence, an mRNA pseudoknot | 28107647 |
| 2016-04-30 10:40:00 | The distal N-terminal metal-binding domain transfers copper to the membrane-integral ion-binding sites of CopA, while the proximal metal-binding domain has a regulatory role by suppressing the catalytic activity of CopA in absence of copper. | 25899340 |
| 2016-03-19 10:16:00 | Data indicate that RNAP sigma(70)-can bind to copper efflux regulator (CueR)-promoter PcopA complex. | 26483469 |
| 2010-01-21 00:00:00 | copper-transporting ATPases, CopA and ATP7A, in both bacteria and macrophage are unique determinants of bacteria survival and identify an unexpected role for copper at the host-pathogen interface | 19808669 |
| 2007-11-05 21:39:00 | N-terminus verified by Edman degradation on mature peptide | 9868784 |
| Type | IDs |
|---|---|
| Synonymous | ECK0478, ybaR |
| Gene |
UniProtKB-ID:
COPA_ECOLI
UniprotKB:
Q59385
UniParc:
UPI0000168038,
UPI000BB9FC76
EMBL:
U82664,
U00096,
U58330,
AP009048
EnsemblGenome:
BAE76263,
b0484
KO:
ecj:JW0473,
eco:b0484
|
| Nucleutide sequences |
EMBL-CDS:
AYC08180.1,
AAB40238.1,
BAE76263.1,
AAC73586.1,
AAB02268.1
EnsemblGenome_TRS:
AAC73586,
BAE76263
|
| Protein sequencees |
EnsemblGenome_PRO:
AAC73586,
BAE76263
RefSeq:
YP_009518752.1,
NP_415017.1
|
| Others |
UniRef100:
UniRef100_Q59385
UniRef90:
UniRef90_Q59385
UniRef50:
UniRef50_Q59385
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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