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946096 prc

946096

prc

tail-specific protease

protein-coding

Escherichia coli str. K-12 substr. MG1655

基因描述

Type Description
Definition tail-specific protease

研究结论

Date Results Publications
2020-06-06 13:32:00 We demonstrated for the first time that Prc is essential for full Extraintestinal pathogenic E. coli (ExPEC) virulence in urinary tract infections. Our results collectively support the idea that Prc is essential for bacterial envelope integrity, thus explaining how Prc deficiency results in an attenuated ExPEC. 31900139
2020-05-02 10:51:00 In Prc, a hydrophobic substrate sensor engages substrate binding to the PDZ domain and triggers a structural remodeling to align the active-site residues. 31387902
2018-10-06 10:30:00 A proteolytic system comprising the periplasmic PDZ-protease Prc and the lipoprotein adaptor NlpI contributes to Peptidoglycan (PG) enlargement. 29138488
2014-04-19 10:05:00 ProQ and Prc deficiencies lowered the ProP activity of bacteria cultivated at moderate salinity by approximately 70% and 30%, respectively, but did not affect other osmoregulatory functions. 24443528
2007-11-05 21:38:00 N-terminus verified by Edman degradation on mature peptide 1729701

名称对应

Type IDs
Synonymous ECK1829, tsp
Gene
UniProtKB-ID: PRC_ECOLI
UniprotKB: P23865
UniParc: UPI0000132178
EMBL: D00674, AP009048, S49803, U00096, L48409, M75634
EnsemblGenome: b1830, BAA15638
KO: ecj:JW1819, eco:b1830
Nucleutide sequences
EMBL-CDS: BAA00578.1, AAD41528.1, AAB24313.1, AAA24699.1, BAA15638.1, AAC74900.1, BAA00577.1
EnsemblGenome_TRS: BAA15638, AAC74900
Protein sequencees
EnsemblGenome_PRO: BAA15638, AAC74900
RefSeq: NP_416344.1
Others
UniRef100: UniRef100_P23865
UniRef90: UniRef90_P23865
UniRef50: UniRef50_P23865

全选

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研究热度

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