| Type | Description |
|---|---|
| Definition | antitoxin of the MqsRA toxin-antitoxin system/DNA-binding transcriptional repressor MqsA |
| Date | Results | Publications |
|---|---|---|
| 2016-10-29 11:58:00 | findings show that the cyclic AMP receptor protein (CRP) indirectly upregulates mqsRA transcription; also show that CRP plays an important role in antibiotic persistence, which seems to be partially mediated through MqsRA | 26408451 |
| 2013-01-12 10:02:00 | two well-defined domains of MqsA have almost identical structure in solution and in the two published crystal structures of dimeric MqsA bound to either MqsR or DNA | 22789559 |
| 2011-07-30 11:05:00 | Upon oxidative stress, MqsA is rapidly degraded by Lon protease, resulting in induction of rpoS; degradation of antitoxins during stress leads to a switch from the planktonic state (high motility) to the biofilm state (low motility). | 21516113 |
| 2011-01-29 11:24:00 | solvent content of the crystal was consistent with the presence of two MqsA molecules bound to the duplex DNA in the asymmetric unit | 20823526 |
| 2010-10-23 11:13:00 | The MqsR/MqsA TA system controls cell physiology via its own toxicity as well as through its regulation of another toxin, CspD. | 20105222 |
| Type | IDs |
|---|---|
| Synonymous | ECK3012, ygiT |
| Gene |
UniProtKB-ID:
MQSA_ECOLI
UniprotKB:
Q46864
UniParc:
UPI000013B0CC
EMBL:
U28377,
U00096,
AP009048
EnsemblGenome:
BAE77077,
b3021
KO:
eco:b3021,
ecj:JW2989
|
| Nucleutide sequences |
EMBL-CDS:
BAE77077.1,
AAC76057.1,
AAA69189.1
EnsemblGenome_TRS:
AAC76057,
BAE77077
|
| Protein sequencees |
EnsemblGenome_PRO:
AAC76057,
BAE77077
RefSeq:
NP_417493.1
|
| Others |
UniRef100:
UniRef100_Q46864
UniRef90:
UniRef90_Q46864
UniRef50:
UniRef50_Q46864
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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