| Type | Description |
|---|---|
| Definition | dihydroorotase |
| Date | Results | Publications |
|---|---|---|
| 2010-01-21 00:00:00 | The kinetic and structural analyses suggest that Thr109 and Thr110 in the flexible loop provide productive binding of substrate and stabilize the transition-state intermediate, thereby increasing catalytic activity. | 17711307 |
| 2010-01-21 00:00:00 | Results show that a loop comprised of residues 105-115 of dihydroorotase has different conformations in its two subunits. | 15826651 |
| 2010-01-21 00:00:00 | we report the structures of Escherichia coli DHOase crystallized without ligand (1.7 A resolution) and in the presence of the inhibitors 2-oxo-1,2,3,6-tetrahydropyrimidine-4,6-dicarboxylate (2.0 A) and 5-fluoroorotate (2.2 A). | 17550785 |
| 2010-01-21 00:00:00 | DAta show that expression of chromosomal dihydroorotase activity and beta-galactosidase activity of pyrC-lacZ fusion plasmid was repressed to about 30% and 17%, respectively in the fur+ strain compared to those in the fur- strain. | 18176545 |
| 2007-11-05 21:38:00 | N-terminus verified by Edman degradation on mature peptide | 9298646 |
| Type | IDs |
|---|---|
| Synonymous | ECK1047 |
| Gene |
UniProtKB-ID:
PYRC_ECOLI
UniprotKB:
P05020
UniParc:
UPI0000168075
EMBL:
D31709,
U00096,
M16752,
X04469,
AP009048
EnsemblGenome:
b1062,
BAA35870
KO:
eco:b1062,
ecj:JW1049
|
| Nucleutide sequences |
EMBL-CDS:
BAA35870.1,
AAC74146.1,
AAA24482.1,
CAA28157.1,
BAA06514.1
EnsemblGenome_TRS:
BAA35870,
AAC74146
|
| Protein sequencees |
EnsemblGenome_PRO:
AAC74146,
BAA35870
RefSeq:
NP_415580.1
|
| Others |
UniRef100:
UniRef100_C4ZS02
UniRef90:
UniRef90_Q8X8N8
UniRef50:
UniRef50_P06204
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| 1 |
University of Sydney |
4 |
| 2 |
University of Alabama |
2 |
| 3 |
University of Alabama at Birmingham 35294. |
2 |
| 4 |
Texas A&M University |
2 |
| 5 |
Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain. |
1 |
| 排名 | 研究人员 | 文献 |
|---|---|---|
| 1 |
C L Turnbough |
5 |
| 2 |
K D Collins |
4 |
| 3 |
Megan J Maher |
4 |
| 4 |
Mihwa Lee |
4 |
| 5 |
J Mitchell Guss |
4 |