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945711 csgE

945711

csgE

curli transport specificity factor

protein-coding

Escherichia coli str. K-12 substr. MG1655

基因描述

Type Description
Definition curli transport specificity factor

研究结论

Date Results Publications
2019-07-27 12:08:00 A region of positive charge formed by the confluence of the beta1-beta2 and beta3-alpha2 loops at the head of Curli transport specificity factor CsgE plays a key role in the CsgE-CsgA (amyloidogenic CsgA) interaction and is required for curli assembly. These mechanistic insights into the directed assembly of functional amyloids in extracellular biofilms elucidate possible targets for biofilm-associated bacterial infect... 30018113
2017-08-19 11:20:00 The electro-negative and flexible tail of CsgE can adjust toward the electro-positive patches on the CsgG interface as the initial step in binding. 27298344
2017-07-22 11:16:00 Studies show the common structural features of CsgC and CsgE and the potential implications for general inhibition of amyloid. 27913673
2016-04-16 10:45:00 determined regions involved in CsgE self-association and on the basis of that, prepared a double mutant W48A/F79A, derived from interface alanine scan, and verified that it exists as a monomer 26418947

名称对应

Type IDs
Synonymous ECK1025
Gene
UniProtKB-ID: CSGE_ECOLI
UniprotKB: P0AE95
UniParc: UPI0000128531
EMBL: X90754, AP009048, U00096, AF081826
EnsemblGenome: b1039, BAA35820
KO: ecj:JW1022, eco:b1039
Nucleutide sequences
EMBL-CDS: CAA62279.1, BAA35820.1, AAD16024.1, AAC74123.1
EnsemblGenome_TRS: AAC74123, BAA35820
Protein sequencees
EnsemblGenome_PRO: AAC74123, BAA35820
RefSeq: NP_415557.1
Others
UniRef100: UniRef100_P0AE97
UniRef90: UniRef90_P0AE97
UniRef50: UniRef50_P0AE97

全选

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研究热度

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