| Type | Description |
|---|---|
| Definition | isocitrate dehydrogenase |
| Date | Results | Publications |
|---|---|---|
| 2019-09-14 10:43:00 | GltA, icd and mdh do not form a transcription unit, are scattered around the chromosome and are expressed from different promoters. | 29546354 |
| 2017-02-18 10:23:00 | introduced single point mutations (Arg153His, Arg153Cys); both the R153H and R153C mutants nearly lost wild-type IDH activity yet acquired the neomorphic ability to catalyze the conversion of alpha-ketoglutarate to 2-hydroxyglutarate | 27406240 |
| 2013-04-27 10:35:00 | Dimerization and bifunctionality confer robustness to the isocitrate dehydrogenase regulatory system in Escherichia coli | 23192354 |
| 2010-01-21 00:00:00 | control of catalytic activity by phosphorylation [review] | 16415587 |
| 2007-11-05 21:38:00 | N-terminus verified by Edman degradation on complete protein | 9298646 |
| Type | IDs |
|---|---|
| Synonymous | ECK1122, icdA, icdE |
| Gene |
UniProtKB-ID:
IDH_ECOLI
UniprotKB:
P08200
UniParc:
UPI000011050D
EMBL:
U00096,
AF017587,
AP009048,
J02799
EnsemblGenome:
BAA35958,
b1136
KO:
ecj:JW1122,
eco:b1136
|
| Nucleutide sequences |
EMBL-CDS:
AAC45887.1,
BAA35958.1,
AAC74220.1,
AAA24006.1
EnsemblGenome_TRS:
BAA35958,
AAC74220
|
| Protein sequencees |
EnsemblGenome_PRO:
BAA35958,
AAC74220
RefSeq:
NP_415654.1
|
| Others |
UniRef100:
UniRef100_P08200
UniRef90:
UniRef90_P08200
UniRef50:
UniRef50_P08200
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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