| Type | Description |
|---|---|
| Definition | protein-lysine deacetylase/desuccinylase |
| Date | Results | Publications |
|---|---|---|
| 2018-05-12 11:14:00 | discovered that CobB acts as a lipoamidase; results indicate that CobB has the ability to regulate pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase activity under different growth conditions | 28900027 |
| 2015-10-24 11:12:00 | CobB can reverse acetylation regardless of acetyl donor or acetylation mechanism. | 25417765 |
| 2014-08-09 10:45:00 | CobB is a bifunctional enzyme with lysine desuccinylation and deacetylation activities. | 24176774 |
| 2012-02-25 10:54:00 | CobB play crucial roles in the transcription regulation of the periplasmic stress-responsive promoter cpxP when cells of Escherichia coli grow in the presence of glucose, an environment that induces protein acetylation | 21696463 |
| 2011-01-15 10:32:00 | Results suggest that CobB regulates E. coli chemotaxis by deacetylating CheY. | 20345663 |
| Type | IDs |
|---|---|
| Synonymous | ECK1106, ycfY |
| Gene |
UniProtKB-ID:
NPD_ECOLI
UniprotKB:
P75960
UniParc:
UPI0001DC49C4,
UPI0000127DC6
EMBL:
AP009048,
U00096
EnsemblGenome:
b1120,
BAA35940
KO:
eco:b1120,
ecj:JW1106
|
| Nucleutide sequences |
EMBL-CDS:
BAA35940.1,
AAC74204.2
EnsemblGenome_TRS:
BAA35940,
AAC74204
|
| Protein sequencees |
EnsemblGenome_PRO:
BAA35940,
AAC74204
RefSeq:
NP_415638.3
|
| Others |
UniRef100:
UniRef100_P75960
UniRef90:
UniRef90_P75960
UniRef50:
UniRef50_P75960
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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