| Type | Description |
|---|---|
| Definition | transcription-repair coupling factor |
| Date | Results | Publications |
|---|---|---|
| 2019-01-05 10:08:00 | Mfd can locate a stalled/paused transcription elongation complex via a release and catch-up mechanism. Depending on load, Mfd either rescues a backtracked TEC or terminates transcription. | 29224782 |
| 2018-12-22 11:27:00 | The results reveal that bacterial RNA polymerase is frequently rescued by Mfd during normal growth and highlight a ubiquitous house-keeping role for Mfd in regulating transcription elongation. | 29679003 |
| 2014-05-31 11:16:00 | Mfd, which is an ATP-dependent superfamily 2 helicase that binds to RNAP, continues to translocate along DNA after RNAP has been displaced until a lesion in the template strand is located. | 24554077 |
| 2011-03-26 10:23:00 | TRCF derepression is associated with profound conformational changes that primarily involve a reorganization of the interdomain interactions. | 21185303 |
| 2010-01-21 00:00:00 | preliminary structure determination of Escherichia coli Mfd, the transcription-repair coupling factor | 16511235 |
| Type | IDs |
|---|---|
| Synonymous | ECK1100 |
| Gene |
UniProtKB-ID:
MFD_ECOLI
UniprotKB:
P30958
UniParc:
UPI000012F037
EMBL:
U00096,
AP009048
EnsemblGenome:
BAA35929,
b1114
KO:
ecj:JW1100,
eco:b1114
|
| Nucleutide sequences |
EMBL-CDS:
BAA35929.1,
AAC74198.1
EnsemblGenome_TRS:
AAC74198,
BAA35929
|
| Protein sequencees |
EnsemblGenome_PRO:
AAC74198,
BAA35929
RefSeq:
NP_415632.1
|
| Others |
UniRef100:
UniRef100_P30958
UniRef90:
UniRef90_P30958
UniRef50:
UniRef50_P30958
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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