lolC - lipoprotein release complex - inner membrane subunit-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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945673 lolC

基因描述

Type	Description
Definition	lipoprotein release complex - inner membrane subunit

研究结论

Date	Results	Publications
2017-07-15 10:27:00	Inhibition of LolCDE leads to significant inhibition of growth and lipoprotein transport.	27645386
2011-10-29 10:21:00	These results indicate that the affinity of LolCDE for apolipoprotein is very low, and therefore, overexpression of LolCDE is required for its release and sorting to the outer membrane.	21742870
2010-01-21 00:00:00	suppressor mutations of the lolC gene that correct the growth defect caused by the LolD mutations were mainly located in the periplasmic loop	16585747
2010-01-21 00:00:00	Liganded LolCDE thus reveals molecular events brought about through ATP binding and hydrolysis, LolCDE is the first example of an ABC transporter purified with tightly bound native substrates.	17038124
2010-01-21 00:00:00	interaction sites of LolA, LolB, and LolC which transfer lipoproteins	19307584

名称对应

Type	IDs
Synonymous	ECK1102, ycfU
Gene	UniProtKB-ID: LOLC_ECOLI UniprotKB: P0ADC3 UniParc: UPI000012E7CE EMBL: U00096, AP009048 EnsemblGenome: BAA35936, b1116 KO: ecj:JW5161, eco:b1116
Nucleutide sequences	EMBL-CDS: AAC74200.1, BAA35936.2 EnsemblGenome_TRS: AAC74200, BAA35936
Protein sequencees	EnsemblGenome_PRO: AAC74200, BAA35936 RefSeq: NP_415634.1
Others	UniRef100: UniRef100_P0ADC5 UniRef90: UniRef90_P0ADC5 UniRef50: UniRef50_P0ADC5

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mRNA

Protein

UniprotKB

Description

Refseq

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全选

Pubmed编号	文献信息	发表日期	相关基因
30012603	Insights into bacterial lipoprotein trafficking from a structure of LolA bound to the LolC periplasmic domain. Proc. Natl. Acad. Sci. U.S.A. Elise Kaplan , Nicholas P Greene , Allister Crow , Vassilis Koronakis	2018-07-31	-
27645386	Transcriptional Responses of Escherichia coli to a Small-Molecule Inhibitor of LolCDE, an Essential Component of the Lipoprotein Transport Pathway. J. Bacteriol. Christian Lorenz , Thomas J Dougherty , Stephen Lory	2016-12-01	-
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
21742870	Overexpression of LolCDE allows deletion of the Escherichia coli gene encoding apolipoprotein N-acyltransferase. J. Bacteriol. Shin-ichiro Narita , Hajime Tokuda	2011-09-01	-
19809197	Membrane topology and functional importance of the periplasmic region of ABC transporter LolCDE. Biosci. Biotechnol. Biochem. Masaki Yasuda , Asako Iguchi-Yokoyama , Shin-ichi Matsuyama , Hajime Tokuda , Shin-ichiro Narita	2009-10-01	-
19307584	Model of mouth-to-mouth transfer of bacterial lipoproteins through inner membrane LolC, periplasmic LolA, and outer membrane LolB. Proc Natl Acad Sci U S A Suguru Okuda , Hajime Tokuda	2009-04-07	-
18218629	Molecular events involved in a single cycle of ligand transfer from an ATP binding cassette transporter, LolCDE, to a molecular chaperone, LolA. J Biol Chem Naohiro Taniguchi , Hajime Tokuda	2008-03-28	-
17498646	Diverse effects of phospholipids on lipoprotein sorting and ATP hydrolysis by the ABC transporter LolCDE complex. Biochim. Biophys. Acta Shigehiko Miyamoto , Hajime Tokuda	2007-07-01	-
17309111	Comparison of SDS- and methanol-assisted protein solubilization and digestion methods for Escherichia coli membrane proteome analysis by 2-D LC-MS/MS. Proteomics Nan Zhang , Rui Chen , Nelson Young , David Wishart , Philip Winter , Joel H Weiner , Liang Li	2007-02-01	-
17038124	A novel ligand bound ABC transporter, LolCDE, provides insights into the molecular mechanisms underlying membrane detachment of bacterial lipoproteins. Mol. Microbiol. Yasuko Ito , Kyoko Kanamaru , Naohiro Taniguchi , Shigehiko Miyamoto , Hajime Tokuda	2006-11-01	-

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