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945641 rne

945641

rne

ribonuclease E

protein-coding

Escherichia coli str. K-12 substr. MG1655

基因描述

Type Description
Definition ribonuclease E

研究结论

Date Results Publications
2020-03-21 11:33:00 accumulation of GlmZ* prevents complete GlmZ turnover. This mechanism may serve to adjust a robust glmS basal expression level that is buffered against fluctuations in RapZ availability. 31116083
2020-03-21 10:35:00 we have examined RNase E variants bearing extended C-terminal truncations in combination with substitutions in the active site or 5'-sensor pocket. We show that intragenic or allelic complementation occurs in RNase E, whereby enzyme activity is restored and strains are rendered viable when pairs of individually inactive mutant proteins are mixed together or co-expressed 31802130
2019-10-19 12:19:00 These findings suggest that RNase E searches for cleavage sites by scanning linearly from the 5'-terminal monophosphate along single-stranded regions of RNA and that its progress is impeded by structural discontinuities encountered along the way. 30852060
2019-08-24 11:59:00 Moreover, our assays of MicL, ArcZ and CpxQ showed that sRNAs exhibit differential sensitivity to RNase E, likely a consequence of a hierarchy of sRNA features recognized by the endonuclease. 30462307
2017-07-01 10:46:00 This study suggests that, rather than its role in the processing of any one particular substrate, its distributed functions on all the different substrates (mRNA, rRNA, and tRNA) are responsible for the essentiality of RNase E in E. coli. 28167522

名称对应

Type IDs
Synonymous ECK1069, ams, hmp1, smbB
Gene
UniProtKB-ID: RNE_ECOLI
UniprotKB: P21513
UniParc: UPI0000168078
EMBL: X67470, AP009048, X54309, U00096, M62747, L23942
EnsemblGenome: BAA35893, b1084
KO: eco:b1084, ecj:JW1071
Nucleutide sequences
EMBL-CDS: CAA47818.1, BAA35893.1, AAA03347.1, AAC74168.1, AAA23443.1, CAA38206.1
EnsemblGenome_TRS: AAC74168, BAA35893
Protein sequencees
EnsemblGenome_PRO: AAC74168, BAA35893
RefSeq: NP_415602.1
Others
UniRef100: UniRef100_P21513
UniRef90: UniRef90_P21513
UniRef50: UniRef50_P21513

全选

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