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945602 putP

945602

putP

proline:Na(+) symporter

protein-coding

Escherichia coli str. K-12 substr. MG1655

基因描述

Type Description
Definition proline:Na(+) symporter

研究结论

Date Results Publications
2017-05-27 11:27:00 the results demonstrate that TM6' plays a central role in substrate binding and release on the inner side of the membrane also in PutP and extend the knowledge on functionally relevant amino acids in transporters with a LeuT-type structural fold. 27793991
2011-03-19 10:54:00 Remarkably,as proposed computationally and discovered here experimentally, residues Y140, W244, and Y248 of transmembrane segments 4 and 7 are particularly important for PutP function and are suggested to participate in proline binding and/or gating. 21130773
2010-03-01 11:05:00 backbone models of PutP exhibiting a pronounced kink near residue T341, which is involved in substrate binding, were obtained. The kink may be associated with a hinge that allows the protein to open and close an inwardly oriented cavity. 19134477
2010-01-21 00:00:00 Results describe the function of transmembrane domain IX in the Na+/proline transporter PutP. 18692508
2007-11-05 21:38:00 N-terminus verified by Edman degradation on complete protein 1567896

名称对应

Type IDs
Synonymous ECK1006, putC
Gene
UniProtKB-ID: PUTP_ECOLI
UniprotKB: P07117
UniParc: UPI0000132B86
EMBL: L01150, U00096, M35174, AP009048, L01151, X05653
EnsemblGenome: BAA35793, b1015
KO: eco:b1015, ecj:JW1001
Nucleutide sequences
EMBL-CDS: BAA35793.1, AAA24463.1, AAA24458.1, AAC74100.1, CAA29143.1, AAA24464.1
EnsemblGenome_TRS: AAC74100, BAA35793
Protein sequencees
EnsemblGenome_PRO: BAA35793, AAC74100
RefSeq: NP_415535.1
Others
UniRef100: UniRef100_P07117
UniRef90: UniRef90_P07117
UniRef50: UniRef50_P07117

全选

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