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945548 mukF

945548

mukF

chromosome partitioning protein MukF

protein-coding

Escherichia coli str. K-12 substr. MG1655

基因描述

Type Description
Definition chromosome partitioning protein MukF

研究结论

Date Results Publications
2020-08-15 19:07:00 Organization of the Escherichia coli Chromosome by a MukBEF Axial Core. 32097603
2019-12-07 11:20:00 Complex formation requires functional interactions between the C- and N-terminal domains of MukF with the MukB head and neck, respectively, and MukE, which organizes the complexes by stabilizing binding of MukB heads to MukF. In the absence of head engagement, a MukF dimer bound by MukE forms complexes containing only a dimer of MukB. 31400115
2019-08-17 12:12:00 The authors show that a 4-helix bundle adjacent to the MukF dimerisation domain interacts functionally with the MukB coiled-coiled 'neck' adjacent to the ATPase head. They propose that this interaction leads to an asymmetric tripartite complex, as in other SMC (Structural Maintenance of Chromosomes) complexes. 29323635
2017-05-27 11:50:00 activity of MukB requires DNA binding by the head domains of the protein but does not require either ATP or its partner proteins MukE or MukF. The ability of MukB to mediate DNA catenation underscores its potential for bringing distal regions of a chromosome together. 27697840
2016-06-11 10:54:00 MatP regulates the action of topoisomerase IV and MukBEF in chromosome segregation. 26818444

名称对应

Type IDs
Synonymous ECK0913, kicB
Gene
UniProtKB-ID: MUKF_ECOLI
UniprotKB: P60293
UniParc: UPI000012F8F2
EMBL: U00096, AP009048, D26440
EnsemblGenome: b0922, BAA35668
KO: eco:b0922, ecj:JW0905
Nucleutide sequences
EMBL-CDS: BAA35668.1, AAC74008.1, BAA05457.1
EnsemblGenome_TRS: AAC74008, BAA35668
Protein sequencees
EnsemblGenome_PRO: BAA35668, AAC74008
RefSeq: NP_415442.1
Others
UniRef100: UniRef100_A7ZK12
UniRef90: UniRef90_A7ZK12
UniRef50: UniRef50_P45185

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