| Type | Description |
|---|---|
| Definition | formate channel FocA |
| Date | Results | Publications |
|---|---|---|
| 2019-09-28 10:16:00 | Our results suggest that regulation of formate translocation direction by FocA/FocB channels is important for maintaining internal pH and proton motive force by modulating H2 production. | 30247527 |
| 2017-04-29 10:09:00 | in vivo competitive assays showed that one of the second steps (focA) exhibited positive epistasis with the first, while another (dcuB) exhibited negative epistasis. The data shows that strong effect adaptive mutations continuously recur in gut commensal bacterial species. | 27812114 |
| 2015-04-18 10:08:00 | Highly conserved amino acid residues within FocA identified in structural studies are predicted to be important in the control of formate translocation. | 24659605 |
| 2013-05-04 11:43:00 | FocA has a strong preference for formate as a substrate in vivo and not other acidic fermentation products and the tight coupling between FocA and PflB synthesis ensures adequate substrate delivery to the appropriate formate dehydrogenase. | 23335413 |
| 2010-11-06 10:34:00 | Analysis of the oligomeric state by blue-native polyacrylamide gel electrophoresis revealed FocA to have an unexpected pentameric quaternary structure. | 20041954 |
| Type | IDs |
|---|---|
| Synonymous | ECK0895, ycaE |
| Gene |
UniProtKB-ID:
FOCA_ECOLI
UniprotKB:
P0AC23
UniParc:
UPI000012AB35
EMBL:
M26413,
U00096,
AP009048
EnsemblGenome:
BAA35639,
b0904
KO:
eco:b0904,
ecj:JW0887
|
| Nucleutide sequences |
EMBL-CDS:
AAC73990.1,
BAA35639.1,
AAA20390.1
EnsemblGenome_TRS:
AAC73990,
BAA35639
|
| Protein sequencees |
EnsemblGenome_PRO:
AAC73990,
BAA35639
RefSeq:
NP_415424.1
|
| Others |
UniRef100:
UniRef100_P0AC25
UniRef90:
UniRef90_P0AC25
UniRef50:
UniRef50_P0AC25
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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