| Type | Description |
|---|---|
| Definition | homer scaffold protein 2 |
| Date | Results | Publications |
|---|---|---|
| 2019-11-16 13:24:00 | we have identified a distinct, novel insertion variant in HOMER2, which provides validating evidence that HOMER2 is indeed required for normal hearing. Its sequence alteration is responsible for late-onset, autosomal dominant, non-syndromic, SNHL in humans. | 30047143 |
| 2018-11-03 10:07:00 | that HOMER2 may be involved in tumourigenesis of endometrioid uterine tumours | 29891190 |
| 2017-02-18 11:34:00 | Homer1 and Homer2 might be considered as novel diagnostic biomarkers for large-artery atherosclerosis stroke. | 27832625 |
| 2016-01-23 11:27:00 | This study showed that HOMER2 (rs1256429; intronic, p = 8.7 x 10(1)) associated with Alzheimer disease. | 25649652 |
| 2016-01-02 11:11:00 | These data provide compelling evidence that HOMER2 is required for normal hearing and that its sequence alteration in humans leads to ADNSHL through a dominant-negative mode of action | 25816005 |
| Type | IDs |
|---|---|
| Synonymous | ACPD, CPD, DFNA68, HOMER-2, VESL-2 |
| Gene |
UniProtKB-ID:
HOME2_HUMAN
UniprotKB:
Q9NSB8
UniParc:
UPI0000073D6D,
UPI000006D53F
EMBL:
AF081530,
AC022558,
Y19028,
BC012109,
AF093263,
Y19026,
AF093264,
Y19025,
AC044907,
Y19027
Ensembl:
ENSG00000103942
KO:
hsa:9455
|
| Nucleutide sequences |
EMBL-CDS:
CAB75537.1,
AAH12109.1,
AAD13748.1,
AAC71027.1,
AAC71028.1,
CAB75538.1,
CAB75540.1,
CAB75539.1
Ensembl_TRS:
ENST00000450735,
ENST00000304231
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000407634,
ENSP00000305632
RefSeq:
XP_011520533.1,
XP_005272506.1,
XP_011520535.1,
XP_011520534.1,
XP_006720839.1,
NP_004830.2,
XP_005272505.1,
XP_011520536.1,
XP_006720838.1,
NP_955362.1
|
| Others |
UniRef100:
UniRef100_Q9NSB8
UniRef90:
UniRef90_Q9NSB8
UniRef50:
UniRef50_Q9NSB8
UniGene:
Hs.578443
CCDS:
CCDS45336.1,
CCDS45334.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员