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945483 nfsA

945483

nfsA

NADPH-dependent nitroreductase NfsA

protein-coding

Escherichia coli str. K-12 substr. MG1655

基因描述

Type Description
Definition NADPH-dependent nitroreductase NfsA

研究结论

Date Results Publications
2018-11-24 11:53:00 Mutations in nfsA and nfsB were the main mechanisms leading to nitrofurantoin resistance, and overexpression of the oqxAB gene might help to further increase the minimum inhibitory concentrations of nitrofurantoin. 29753133
2017-05-20 10:29:00 reduction of quinones by NfsA is most consistent with a single-step (H(-)) hydride transfer mechanism 27986535
2014-04-19 11:18:00 Findings revealed that Phe42 is important for maintaining NfsA activity and structure. 23801116
2012-06-30 11:19:00 NfsA and NfsB, but not NemA, are responsible for the conversion of ethyl 2-(2'-nitrophenoxy)acetate. 22173483

名称对应

Type IDs
Synonymous ECK0842, mda18, mdaA, ybjB
Gene
UniProtKB-ID: NFSA_ECOLI
UniprotKB: P17117
UniParc: UPI00000480E3
EMBL: D38308, X15859, U18655, U00096, AP009048
EnsemblGenome: b0851, BAA35562
KO: ecj:JW0835, eco:b0851
Nucleutide sequences
EMBL-CDS: CAA33867.1, AAC43450.1, BAA07425.1, BAA35562.1, AAC73938.1
EnsemblGenome_TRS: BAA35562, AAC73938
Protein sequencees
EnsemblGenome_PRO: AAC73938, BAA35562
RefSeq: NP_415372.1
Others
UniRef100: UniRef100_P17117
UniRef90: UniRef90_P17117
UniRef50: UniRef50_P17117

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