| Type | Description |
|---|---|
| Definition | multidrug efflux pump RND permease AcrD |
| Date | Results | Publications |
|---|---|---|
| 2017-01-28 10:33:00 | AcrBA-TolC complex becomes unstable upon the induction of AcrD, which presumably replaces AcrB in the ternary complex. Such instability is suppressed upon the addition of AcrB-specific substrates. The assembly of resistance-nodulation-cell division-type efflux system is a regulated dynamic process that provides bacteria with a highly flexible repertoire of survival strategies to cope with a wide spectrum of antibiotics. | 26916090 |
| 2016-01-16 11:59:00 | multiple deletion of acrB, acrD, and mdtABC resulted in a significant decrease in enterobactin export and that plasmids carrying the acrAB, acrD, or mdtABC genes restored the decrease in enterobactin export exhibited by the DeltaacrB acrD mdtABC mutant. | 25259870 |
| 2010-01-21 00:00:00 | AcrD can also capture aminoglycosides from the periplasm to extrude them into the medium in intact cells, acting as a "periplasmic vacuum cleaner." | 15743938 |
| Type | IDs |
|---|---|
| Synonymous | ECK2465, yffA |
| Gene |
UniProtKB-ID:
ACRD_ECOLI
UniprotKB:
P24177
UniParc:
UPI0000125398
EMBL:
AP009048,
U00096,
X57403,
U10436,
U12598
EnsemblGenome:
BAA16344,
b2470
KO:
ecj:JW2454,
eco:b2470
|
| Nucleutide sequences |
EMBL-CDS:
AAA74741.1,
AAC75523.1,
AAA20584.1,
CAA40663.1,
BAA16344.1
EnsemblGenome_TRS:
AAC75523,
BAA16344
|
| Protein sequencees |
EnsemblGenome_PRO:
BAA16344,
AAC75523
RefSeq:
NP_416965.1
|
| Others |
UniRef100:
UniRef100_P24177
UniRef90:
UniRef90_P24177
UniRef50:
UniRef50_P24177
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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