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9454 HOMER3

9454

HOMER3

homer scaffold protein 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition homer scaffold protein 3

研究结论

Date Results Publications
2016-04-09 11:28:00 Homer3 acts as a scaffold that spatially organizes actin assembly to support neutrophil polarity and motility downstream of GPCR activation. 25739453
2015-02-14 12:27:00 Interaction of the protein with amyloid precursor protein is regulated by calcium homeostasis. 24792907
2013-10-26 12:40:00 Loss of Homer3 is associated with acute myeloid leukemia. 23725168
2010-10-30 10:43:00 Homer3 specifically associates with a novel ubiquitin-like domain in the I kappa B kinase (IKK) beta subunit of the IKK complex. 20693425
2010-01-21 00:00:00 study found that Homer2 and Homer3 are negative regulators of T cell activation; this is achieved through binding of nuclear factor of activated T cells (NFAT) and by competing with calcineurin 18218901

名称对应

Type IDs
Synonymous HOMER-3, VESL3
Gene
UniProtKB-ID: HOME3_HUMAN
UniprotKB: Q9NSC5
UniParc: UPI0000073182, UPI000006D7F3, UPI000013C7B0, UPI0000140C32, UPI0000070334
EMBL: AC002985, BC012113, AK124450, CH471106, AK313995, Y17573, Y18895, AF093265, Y18894, Y18896
Ensembl: ENSG00000051128
KO: hsa:9454
Nucleutide sequences
EMBL-CDS: CAB75545.1, CAB75536.1, CAB75543.1, BAG54040.1, CAB75544.1, BAG36707.1, AAH12113.1, AAC71029.1, AAB81545.1, EAW84763.1
Ensembl_TRS: ENST00000433218, ENST00000392351, ENST00000542541, ENST00000539827, ENST00000594439, ENST00000221222
Protein sequencees
Ensembl_PRO: ENSP00000221222, ENSP00000396154, ENSP00000471835, ENSP00000376162, ENSP00000446026, ENSP00000439937
RefSeq: NP_001139194.1, NP_001139196.1, XP_006723006.1, NP_001139193.1, XP_006723007.1, NP_004829.3
Others
UniRef100: UniRef100_Q9NSC5
UniRef90: UniRef90_Q9NSC5
UniRef50: UniRef50_Q9NSC5
UniGene: Hs.720208
CCDS: CCDS46022.1, CCDS12391.1, CCDS46023.1

全选

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