| Type | Description |
|---|---|
| Definition | biotin synthase |
| Date | Results | Publications |
|---|---|---|
| 2011-11-05 11:11:00 | In biotin synthase, abstraction of a hydrogen atom from the C9 methyl group of dethiobiotin results in formation of a dethiobiotinyl methylene carbon radical, which is quenched by a sulfur atom to form a new carbon-sulfur bond in 9-mercaptodethiobiotin. | 21859080 |
| 2010-04-12 12:18:00 | Asparagine 153 and aspartate 155 of bioB are important for retaining intermediates during the catalytic cycle. | 19199517 |
| 2010-01-21 00:00:00 | mutants of highly conserved residues from the Y(150)NHNLD motif are inactive & are also unable to cleave AdoMet and to produce the deoxyadenosyl radical (AdoCH(2)(*)). | 17014080 |
| 2010-01-21 00:00:00 | It is proposed that the [2Fe-2S]2+ cluster of biotin synthase is both the sulfur-donating substrate and the sulfur-oxidizing cofactor, but each round of catalysis generates an inactive enzyme in which this cluster has been destroyed. | 18155152 |
| 2010-01-21 00:00:00 | mutations in the conserved YNHNLD sequence of Escherichia coli BioB affect the formation and stability of the [4Fe-4S](1+) cluster on reduction with dithionite and report the observation of a new [2Fe-2S](1+) cluster. | 19245793 |
| Type | IDs |
|---|---|
| Synonymous | ECK0764 |
| Gene |
UniProtKB-ID:
BIOB_ECOLI
UniprotKB:
P12996
UniParc:
UPI000002C675
EMBL:
AP009048,
A11530,
U00096,
J04423
EnsemblGenome:
b0775,
BAE76362
KO:
ecj:JW0758,
eco:b0775
|
| Nucleutide sequences |
EMBL-CDS:
BAE76362.1,
AAC73862.1,
AAA23515.1,
CAA00965.1
EnsemblGenome_TRS:
AAC73862,
BAE76362
|
| Protein sequencees |
EnsemblGenome_PRO:
AAC73862,
BAE76362
RefSeq:
NP_415296.1
|
| Others |
UniRef100:
UniRef100_A7ZJI4
UniRef90:
UniRef90_Q8X825
UniRef50:
UniRef50_Q7N6Q7
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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