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945285 nagC

945285

nagC

DNA-binding transcriptional dual regulator NagC

protein-coding

Escherichia coli str. K-12 substr. MG1655

基因描述

Type Description
Definition DNA-binding transcriptional dual regulator NagC

研究结论

Date Results Publications
2020-05-09 11:12:00 The NagC mutants exhibiting this paradoxical behaviour have basic amino acids, arginine or lysine, at two critical positions of the recognition helix. 31107208
2015-03-21 10:48:00 This work identifies four amino acids in the linker region which allow NagC to distinguish between a C/G and an A/T bp at positions +/-11 of the operators. 25452338
2010-01-21 00:00:00 Results show that changes at either of two Mlc operators upstream of ptsG are sufficient to lose regulation by Mlc but that both types of changes in both operators are necessary to convert ptsG to a gene regulated by NagC. 18469102
2010-01-21 00:00:00 NagC binds to a single, high-affinity site overlapping the promoter of galP. 19007420
2010-01-21 00:00:00 Mutations in NagC, at positions which form a structural motif resembling a glucose binding site in Mlc, produce permanently repressing forms of NagC, suggesting that this motif forms a N-acetylglucosamine 6-phosphate binding site in NagC. 18067539

名称对应

Type IDs
Synonymous ECK0664, nagR
Gene
UniProtKB-ID: NAGC_ECOLI
UniprotKB: P0AF20
UniParc: UPI000012FD07
EMBL: AF052007, U00096, X14135, AP009048
EnsemblGenome: BAA35319, b0676
KO: eco:b0676, ecj:JW0662
Nucleutide sequences
EMBL-CDS: BAA35319.1, AAC09326.1, AAC73770.1, CAA32354.1
EnsemblGenome_TRS: AAC73770, BAA35319
Protein sequencees
EnsemblGenome_PRO: AAC73770, BAA35319
RefSeq: NP_415202.1
Others
UniRef100: UniRef100_P0AF22
UniRef90: UniRef90_P0AF22
UniRef50: UniRef50_P0AF22

全选

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